中医药导报2025，Vol.31Issue(12)：248-254,7.DOI:10.13862/j.cn43-1446/r.2025.12.039
基于文献计量和知识图谱的中医药防治慢性疲劳综合征可视化分析
Visual Analysis of Traditional Chinese Medicine in the Prevention and Treatment of Chronic Fatigue Syndrome Based on Bibliometrics and Knowledge Mapping
摘要
Abstract
Objective:To analyze the research status and development trends of traditional Chinese medicine(TCM)in the prevention and treatment of chronic fatigue syndrome(CFS)based on bibliometrics and knowledge graph,so as to provide a reference for further research.Methods:Literatures related to TCM prevention and treatment of CFS published from the establishment of databases to January 5,2025 were retrieved from China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform(Wanfang Data),China Science and Technology Journal Database(CSTJ)and China Biomedical Literature Service System(SinoMed),and screened according to inclusion and exclusion criteria.CiteSpace 6.4.R1(64-bit)Advanced was used to display and analyze the annual number of publications,author and institutional cooperation network maps,and keyword knowledge graphs.Results:A total of 2,299 literatures were included,and the annual number of publications showed an overall upward trend.The core author team had not yet been formed(104 core authors,accounting for 40.6%of total publications),and major research institutions were concentrated in Guangzhou,Chengdu,Beijing and other regions.Visual analysis showed that high-frequency TCM therapies included acupuncture/electroacupuncture(215 papers),herbal prescriptions(such as Buzhong Yiqi Decoction(补中益气汤),Xiaoyao Powder(逍遥散),etc.),moxibustion(82 papers),tuina massage(100 papers),and etc.In recent years,characteristic therapies such as ginger-partitioned moxibustion and Tai Chi have emerged as strong research hotspots.High-frequency TCM syndrome patterns included liver depression and spleen deficiency(66 articles),spleen-kidney yang deficiency,and heart-spleen deficiency.Qi deficiency and Yang deficiency constitutions were the main focuses in constitution research.Intestinal flora was a strong burst indicator,which together with immune function and the Hypothalamic-Pituitany-Adrend(HPA)axis constituted the main research directions of biological mechanisms.Network pharmacology and data mining had become emerging research methods.The cooperation density between teams and institutions was low(density=0.0013),and cross-regional cooperation was insufficient.Conclusion:The research on TCM prevention and treatment of CFS presents the trends of diversified therapies,refined syndrome differentiation,in-depth mechanism research and modernized research methods.Future research should deepen the correlation research of"syndrome type-therapy-mechanism",strengthen cross-institutional and multi-center cooperation to optimize diagnosis and treatment schemes,promote the in-depth integration of modern research methods and traditional experience,improve clinical efficacy,and facilitate the formation of scientific and unified diagnosis and treatment standards.关键词
慢性疲劳综合征/中医药/知识图谱/CiteSpace/可视化分析Key words
chronic fatigue syndrome/traditional Chinese medicine/knowledge graph/CiteSpace/visual analysis分类
医药卫生引用本文复制引用
杨昭芸,杨帅,赵广森,胡彧铭,程雅婕,吕沛宛..基于文献计量和知识图谱的中医药防治慢性疲劳综合征可视化分析[J].中医药导报,2025,31(12):248-254,7.基金项目
河南省"双一流"创建学科中医学科学研究专项(HSRP-DFCTCM-2023-2-20) （HSRP-DFCTCM-2023-2-20）
