口腔颌面外科杂志2025，Vol.35Issue(6)：463-470,8.DOI:10.12439/kqhm.1005-4979.2025.06.006
内镜手术与传统手术对下颌下腺良性肿瘤治疗效果的Meta分析
Meta-analysis of the efficacy of endoscopic surgery and traditional surgery in the treatment of submandibular gland benign tumors
摘要
Abstract
Objective:To systematically evaluate the clinical efficacy of endoscopic versus conventional surgery for the treatment of benign submandibular gland tumors.Methods:Databases including China National Knowledge Infrastructure(CNKI),China Biomedical Literature Database(CBM),VIP,Wanfang,PubMed,EMBase,and the Cochrane Library were searched according to the search strategy,with the search period up to January 1,2024.Two independent reviewers assessed the quality of the included studies using the Newcastle-Ottawa scale(NOS),and a Meta-analysis was subsequently performed.Results:A total of 9 studies were included,comprising 1 randomized controlled trial(RCT)and 8 non-randomized controlled trial(nRCT),with a total of 356 patients,153 in the endoscopic group and 203 in the traditional group.Meta-analysis results indicated that the endoscopic group had a significantly longer operative time than the traditional group[weighted mean difference(WMD)=13.56 min;95%confidence interval(CI)=9.36 to 17.75 min;P<0.001].However,the endoscopic approach demonstrated superior outcomes in postoperative satisfaction(WMD=2.85;95%CI=2.03 to 3.67;P<0.001),incision length(WMD=‒17.60 mm;95%CI=‒30.74 to ‒4.47 mm;P<0.01),and intraoperative blood loss(WMD=‒16.32 mL;95%CI=‒26.67 to ‒5.97 mL;P<0.01).No statistically significant differences were observed between the two groups in tumor diameter(WMD=‒0.19 mm;95%CI=-2.91 to 2.54 mm;P=0.89),postoperative drainage volume(WMD=‒5.53 mL;95%CI=‒14.16 to 3.10 mL;P=0.21),the incidence of facial nerve injury[(odds ratio,OR)=0.82;95%CI=0.25 to 2.71;P=0.74],the incidence of great auricular nerve injury(OR=2.40;95%CI=0.36 to 16.18;P=0.37),or the average length of stay(WMD=‒1.2 days;95%CI=‒3.25 to 0.84 days;P=0.25).Conclusion:Based on the current limited evidence,endoscopic surgery for benign submandibular gland tumors can significantly shorten incision length,reduce intraoperative blood loss,and improve postoperative patient satisfaction,but prolongs operative time.关键词
下颌下腺/内镜手术/传统手术/Meta分析Key words
submandibular gland/endoscopic surgery/traditional surgery/Meta-analysis分类
医药卫生引用本文复制引用
李萧倩,周相宇,彭艺琳,李兴旺,许辉,石亮..内镜手术与传统手术对下颌下腺良性肿瘤治疗效果的Meta分析[J].口腔颌面外科杂志,2025,35(6):463-470,8.基金项目
山东省自然科学基金(ZR2020MH187) （ZR2020MH187）
"天山英才"医药卫生高层次人才培养计划(TSYC202301A049) （TSYC202301A049）
