环境与职业医学2025，Vol.42Issue(11)：1330-1335,1413,7.DOI:10.11836/JEOM25192
郑州市河流中典型药物和个人护理品的污染特征及生态风险评价
Pollution characteristics and ecological risk assessment of typical pharmaceutical and personal care products in Zhengzhou rivers
摘要
Abstract
[Background]The residues of pharmaceutical and personal care products(PPCPs)in aquatic en-vironments have become an increasingly prominent urban pollution issue,attracting widespread attention.The analysis of PPCPs pollution in water environments holds profound implications in Zhengzhou,a strategically important city in central China. [Objective]To analyze the pollution characteristics of PPCPs,such as antidepressants and antibi-otics,in rivers of Zhengzhou and assess associated ecological risk. [Methods]Water samples were collected from three rivers of Zhengzhou,and 13 PPCPs(5 an-tibiotics and 8 antidepressants)were analyzed quantitatively by high performance liquid chro-matography-triple quadrupole mass spectrometry(HPLC-MS/MS)after automatic solid phase ex-traction.Risk quotient(RQ)was applied to assess ecological risk of PPCPs with high concentration. [Results]The primary antibiotics pollutants were norfloxacin and ofloxacin,both with a detection rate of 100%.Among antidepressants,venlafaxine and citalopram showed the highest detection rates at 92.3%and 88.5%,respectively.The detected antibiotics with the highest average concentrations included ofloxacin and sulfamethoxazole with concentrations of 99.8 ng·L-1 and 96.2 ng·L-1,respectively,while antidepressants venlafaxine and citalopram were detected with the highest average concentrations of 15.2 ng·L-1and 1.35 ng·L-1,respectively.The inter-river comparisons revealed statistically significant differences in contaminant loads(P<0.05).The sums of average PPCP concentrations at sampling points in the Jialu River and Suoxu River were 83.4 ng·L-1 and 100.4 ng·L-1,respectively.The Xiaoqing River exhibited higher pollution levels than both the Jialu and Suoxu Rivers,with a total average con-centration of 478.4 ng·L-1,where ofloxacin and sulfamethoxazole were identified as the predominant pollutants.The results of ecological risk assessment indicated the RQ contributed by sulfamethoxazole ranged between 0.50-0.95 in the Xiaoqing River,suggesting a control-lable risk but requiring prioritized mitigation strategies.The RQ values of norfloxacin were distributed within the range of 0.10-0.30,indi-cating a moderate ecological risk.The RQ values for ofloxacin and venlafaxine remained below 0.10,indicating a lower risk level. [Conclusion]PPCPs contamination is positive in the rivers of Zhengzhou,and sulfamethoxazole and ofloxacin are the primary cantami-nants.The Xiaoqing River exhibits the highest pollution levels.The initial risk assessment show that sulfamethoxazole and norfloxacin pose potential ecological risks,requiring prioritized contamination management.关键词
河流/药品和个人护理品/污染分析/生态风险评价Key words
river/pharmaceutical and personal care products/pollution analysis/ecological risk assessment分类
医药卫生引用本文复制引用
王谢,马青青,卢素格,刘红丽,苏永恒,韩志伟,张聪恪..郑州市河流中典型药物和个人护理品的污染特征及生态风险评价[J].环境与职业医学,2025,42(11):1330-1335,1413,7.基金项目
河南省医学科技攻关计划项目(LHGJ20230627,LHGJ20250134) （LHGJ20230627,LHGJ20250134）
