临床输血与检验2025，Vol.27Issue(6)：796-801,6.DOI:10.3969/j.issn.1671-2587.2025.06.008
毛细管超速离心法分离鉴定RhCcEe抗原分型混合视野患者的配合性输注效果分析
Analysis of the Effect of RhCcEe Phenotype-matched Transfusion in Patients with RhCcEe Mixed-field Phenotype Identified by Capillary Ultracentrifugation
宋志群 1李莺 1朱雯雯 1孙小红 1周小玉1
作者信息
- 1. 南京医科大学第一附属医院输血科,江苏南京 210029
- 折叠
摘要
Abstract
Objective To explore the value of capillary ultracentrifugation for RhCcEe phenotype identification in patients with mixedfield agglutination reaction(MF).Methods A total of 1 155 patients with MF in RhCcEe phenotype identification from December 2020 to April 2024 were enrolled at First Affiliated Hospital of Nanjing Medical University.The young erythrocytes were separated by capillary ultracentrifugation and identified the RhCcEe antigen,then retrospectively analyzed the RhCcEe antigen compatibility of recipients and donors.Results The distribution of Rh blood groups in 995(86.15％)patients successfully identified by capillary ultracentrifugation was CCDee＞CcDEe＞ccDEE＞CcDee.The proportion of RhCcEe antigen incompatibility transfusion was high(35.41％).When recipients received blood transfusions from multiple donors,their risk of Rh antigen incompatibility transfusion reactions was significantly increased(P＜0.001).Conclusion Capillary ultracentrifugation was helpful for identifying Rh blood groups in patients with MF of RhCcEe antigens and provided the basis for compatible blood transfusion.关键词
毛细管超速离心法/Rh血型鉴定/配合性输注Key words
Capillary ultracentrifugation/Rh blood group identification/Compatible blood transfusion分类
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宋志群,李莺,朱雯雯,孙小红,周小玉..毛细管超速离心法分离鉴定RhCcEe抗原分型混合视野患者的配合性输注效果分析[J].临床输血与检验,2025,27(6):796-801,6.
