护理学报2025，Vol.32Issue(23)：13-18,6.DOI:10.16460/j.issn2097-6569.2025.23.013
分层防控护理干预降低ICU医院感染的经济学评价
Economic evaluation of stratified prevention and control nursing interventions to reduce hospital-ac-quired infections in ICU
摘要
Abstract
Objective To explore the health economic evaluation of a combined model for active screening for multidrug-resistant organisms and the construction of stratified prevention and control nursing in intensive care unit(ICU)in China,and to address the is-sue of emphasizing uniform prevention over stratified approaches.Methods A pre-post comparative design was employed,enrolling 431 inpatients in the ICU from July 1,2023,to September 30,2024.Participants were divided into a control group and an intervention group.The control group received standardized bundled prevention measures,while the intervention group active screening combined with stratified prevention and nursing interventions.hospital-acquired infection incidence of multidrug-resistant bacteria,length of stay,and economic burden were compared between the two groups.Cost-effectiveness analysis and incremental cost-effectiveness ratio were used to evaluate control efficacy.Results The intervention group demonstrated significantly lower rate of hospital-acquired in-fection and multidrug-resistant organism infection compared to the control group.Median total length of stay was reduced by 9 days,and the ICU stay for patients with multidrug-resistant organism infection was shortened by 26 days(P<0.05).The intervention group in-curred an additional cost of¥619 per case compared to the control group.However,direct medical cost,direct non-medical cost,indi-rect economic burden,and disease-related economic burden were lower in the intervention group(P<0.05).The calculated ICER was ¥8,365 per case.Conclusion Nursing-led stratified prevention and control measures for multidrug-resistant organisms in the ICU significantly reduce hospital infection rate and economic burden while demonstrating favorable cost-effectiveness,providing evidence for its implementation in high-risk wards.关键词
护理干预/主动筛查/多重耐药菌/分层防控措施/成本效果分析/医院感染Key words
nursing interventions/active screening/multidrug-resistant organisms/tiered prevention and control measures/cost-ef-fectiveness analysis/hospital-acquired infection分类
医药卫生引用本文复制引用
郭竹英,蒋东贤,谢懿,吴璇,陈芷清,李芸,戴迎春..分层防控护理干预降低ICU医院感染的经济学评价[J].护理学报,2025,32(23):13-18,6.基金项目
广东省卫生经济学课题(2024-WJMF-96) （2024-WJMF-96）
