摘要
Abstract
Objective To study the clinical efficacy of mifepristone combined with methotrexate and laparoscopic surgery in the treatment of ectopic pregnancy,and to analyze its effect on hCG level and pregnancy outcome.Methods Sixty patients with ectopic pregnancy diagnosed and treated in our hospital from July 2022 to July 2024 were selected as the research objects.They were divided into control group and observation group by random number table method,with 30 patients in each group.The control group was treated with mifepristone combined with methotrexate,and the observation group was treated with laparoscopic surgery.The treatment success rate,serum hCG level,clinical symptom improvement time,ovarian function,pregnancy outcome and complication rate were compared between the two groups.Results The success rate of treatment in the observation group(100.00%)was higher than that in the control group(90.00%)(P＜0.05).The serum hCG of the two groups was lower than that before treatment,and the observation group was lower than the control group(P＜0.05).The time of disappearance of abdominal pain,disappearance of vaginal bleeding,recovery of serum hCG and recovery of menstruation in the observation group were shorter than those in the control group(P＜0.05).The ovarian function scores of the two groups were lower than those before treatment,and the observation group was lower than the control group(P＜0.05).After 1 year of follow-up,the intrauterine pregnancy rate of the observation group(63.33%)was higher than that of the control group(43.33%)(P＜0.05).The incidence of complications in the observation group(6.67%)was lower than that in the control group(16.67%)(P＜0.05).Conclusion Mifepristone combined with methotrexate and laparoscopic surgery in the treatment of ectopic pregnancy can achieve a certain effect,but the effect of laparoscopic surgery is more accurate.It can improve the success rate of treatment,greatly reduce the level of hCG,quickly reduce the clinical symptoms of patients,improve the ovarian function and pregnancy outcome of patients,and the incidence of complications is low,the effectiveness and feasibility are better.关键词
米非司酮/甲氨蝶呤/腹腔镜手术/异位妊娠/hCG/妊娠结局Key words
Mifepristone/Methotrexate/Laparoscopic surgery/Ectopic pregnancy/hCG/Pregnancy outcome分类
医药卫生
