摘要
Abstract
Objective To investigate the efficacy and safety of cognitive behavioral therapy(CBT)in the treatment of functional seizures(FS).Methods Databases including PubMed(MEDLINE),EMBASE,and the Cochrane Library were searched for randomized controlled trials(RCTs)on CBT in the treatment of FS published from January 2001 to Octo-ber 2024.Jadad score was used to assess the quality of studies,and stata16 software was used to perform the meta-analysis.Results Four RCTs involving 463 patients were included in this meta-analysis.The analysis showed that CBT could reduce the frequency of FS by≥50%(OR=0.57,95%CI 0.36～0.78,P<0.001),achieve complete remission of sei-zures(OR=1.83,95%CI 1.09～3.05,P=0.021),improve the degree of satisfaction among patients(MD=1.12,95%CI-2.28～0.04,P=0.050),and enhance the quality of life and work(OR=0.50,95%CI 0.47～0.52,P<0.001).Conclusions While CBT can help achieve full remission in FS,more research is needed to confirm its effectiveness in reducing episodes by over 50%and improving patients'quality of life,family functioning,social adaptability,and psycho-logical well-being.关键词
认知行为疗法/治疗/功能性发作/Meta分析Key words
Cognitive behavioral therapy/Treatment/Functional seizures/Meta-analysis分类
医药卫生
