中国康复理论与实践2025，Vol.31Issue(12)：1456-1463,8.DOI:10.3969/j.issn.1006-9771.2025.12.010
中国老年人胃肠道疾病与痴呆的关联:基于CHARLS数据库的分析
Association between gastrointestinal diseases and dementia:an analysis based on CHARLS database
摘要
Abstract
Objective To explore the association between gastrointestinal diseases and dementia among older adults in China. Methods Data were extracted from the 2018 China Health and Retirement Longitudinal Study(CHARLS).Adults aged≥60 years with complete key data were included. Results A total of 6 186 older adults were enrolled,out of whom 32.15%with gastrointestinal diseases and 13.95%with dementia.There was a significant positive correlation between gastrointestinal diseases and dementia(OR=1.178,95%CI 1.001 to 1.384),and this association remained robust after adjusting for confounding factors.Strati-fied analysis showed that the correlation was significant in subgroups of females,urban dweller,primary school education level,history of smokers,no alcohol consumption,individuals with two or more chronic conditions,and those with depressive symptoms.Stratification by age,sleep duration and physical activity metabolism did not significantly alter the association between gastrointestinal diseases and dementia. Conclusion Strengthening the prevention,treatment and management of gastrointestinal diseases in older adults in Chi-na may help reduce the risk of dementia.关键词
胃肠道疾病/痴呆/横断面研究/中国健康与养老追踪调查Key words
gastrointestinal diseases/dementia/cross-sectional study/China Health and Retirement Longitudinal Study分类
医药卫生引用本文复制引用
黄茂茂,邢菲,李丹,王剑雄..中国老年人胃肠道疾病与痴呆的关联:基于CHARLS数据库的分析[J].中国康复理论与实践,2025,31(12):1456-1463,8.基金项目
1.国家自然科学基金青年项目(No.82402958) （No.82402958）
2.四川省科技厅省级科技计划项目(No.24YFFK0377) Supported by National Natural Science Foundation of China(Yonth)(No.82402958),and Sichuan Provincial Science and Technology Department Science and Technology Plan(No.24YFFK0377) （No.24YFFK0377）
