中国全科医学2026，Vol.29Issue(6)：693-698,709,7.DOI:10.12114/j.issn.1007-9572.2024.0391
≥60岁人群中国内脏肥胖指数与心血管代谢性共病关系的横断面研究
A Cross-sectional Study on the Relationship between the Chinese Visceral Adiposity Index and Cardiometabolic Multimorbidity in Individuals Aged 60 and Above
摘要
Abstract
Background With the aging of the population and the increasing prevalence of multimorbidity in China,the high-risk characteristics of cardio-metabolic multimorbidity(CMM)have become an important research field.The exact nature of the relationship between the Chinese visceral adiposity index(CVAI)and CMM remains to be elucidated.Objective This study aims to investigate the relationship between the CVAI and the high risk of CMM,and to evaluate the potential role of CVAI in the prevention and treatment of CMM in the elderly in China.Methods This study was based on the data of 60 029 subjects from the Early Screening and Comprehensive Intervention of High-risk Populations of Cardiovascular Disease in Anhui Province from 2017 to 2021.The demographic information,cardiovascular health status,physical examination and biochemical indicators were analyzed,and the CVAI index was calculated.The subjects were grouped according to the quartile of CVAI(male:T1-T4 group,female:F1-F4 group),and the differences in baseline characteristics were compared.Multtivariate Logistic regression analysis was used to explore the relationship between CVAI and the high risk of CMM.The nonlinear relationship between CVAI and CMM between different genders was assessed by restricted cubic spline(RCS)curves,and a threshold of OR=1 was determined.Results There were 60 029 subjects,including 27 203 males(45.32％)and 32 826 females(54.68％).There were statistically significant differences in age,smoking,drinking,rural area,high school education,BMI,mean arterial pressure(MAP),total cholesterol(TC),triglyceride(TG),high density lipoprotein(HDL-C),fasting plasma glucose(FPG),diabetes,stroke,hypertension,and ischemic heart disease in CVAI quartiles between different genders(P<0.05).There was no significant difference in the history of hypertension medication among males.In women,the difference in medication history of hypertension was statistically significant multivariate.Multtivariate Logistic regression analysis showed that compared with T1(F1)group,the risk of CMM was significantly increased in T2 toT4(F2 to F4)group.After fully adjusting for confounding factors,the T4(F4)group showed the highest risk of CMM in both sexes,male(OR=2.335,95％CI=1.741-3.180,P<0.001),and female(OR=2.735,95％CI=1.778-2.686,P<0.001).There was no significant difference in the odds ratio between different genders.There was no significant difference in the risk of CMM between males in T4 group and females in F4 group(P>0.05).After controlling for different confounding factors,RCS curve suggested that there was a nonlinear relationship between CVAI index and CMM risk in men,and the threshold of OR=1 was 94.75.There was a linear relationship between CVAI index and CMM risk in women,and the threshold of OR=1 was 114.87.Conclusion High level of CVAI may be closely related to the risk of CMM,and the predictive power is consistent in different genders.Special attention should be paid to men with CVAI over 94.75 and women with CVAI over 114.87 to reduce the risk of CMM.关键词
心血管代谢性共病/中国内脏肥胖指数/内脏肥胖指标/肥胖症/安徽省/横截面研究Key words
Cardiometabolic multimorbidity/Chinese visceral adiposity index/Visceral obesity indicator/Obesity/Anhui Province/Cross-sectional study分类
医药卫生引用本文复制引用
韩正,傅方琳,孙梦,潘姚佳,王为强..≥60岁人群中国内脏肥胖指数与心血管代谢性共病关系的横断面研究[J].中国全科医学,2026,29(6):693-698,709,7.基金项目
安徽省科技创新战略与软科学研究专项计划项目(202106f01050042) （202106f01050042）
