中国内镜杂志2025，Vol.31Issue(12)：43-48,6.DOI:10.12235/E20250122
多措施联合的腹腔镜肝切除术治疗肝癌合并肝硬化并门静脉高压症的临床应用研究
Clinical application research on multi-measure laparoscopic liver resection in the treatment of liver cancer complicated with cirrhosis and portal hypertension
摘要
Abstract
Objective To explore the clinical application effect of laparoscopic liver resection(LLR)combined with multiple measures in the treatment of liver cancer patients with cirrhosis and portal hypertension.Methods 60 liver cancer patients with cirrhosis and portal hypertension from October 2022 to July 2024 were selected and randomly divided into two groups.The study group(30 cases)underwent multi-measure combined LLR,while the control group(30 cases)underwent conventional LLR combined with splenectomy and porto-azygous disconnection.Compare the surgery-related conditions(intraoperative blood loss,blood transfusion volume,operation time and hospital stay)of the two groups of patients;The liver functions[glutamic-oxaloacetic transaminase(GOT),total bilirubin(TBiL),and glutamic-pyruvic transaminase(GPT)]and blood routine indicators[platelets(PLT),hemoglobin(Hb),and white blood cells(WBC)]of the two groups of patients before the operation and 7 days after the operation were compared;The occurrence of postoperative complications in the two groups of patients was statistically analyzed.Results The intraoperative blood loss and blood transfusion volume in the study group were significantly less than those in the control group,and the operation time and hospital stay were significantly shorter than those in the control group.The differences were statistically significant(P<0.05).Seven days after the operation,the levels of GPT,TBiL and GOT in both groups were significantly lower than those before the operation,but those in the study group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).Seven days after the operation,the PLT and WBC of both groups were significantly higher than those before the operation,and the PLT of the study group was significantly higher than that of the control group.The differences were statistically significant(P<0.05).There was no statistically significant difference in the total incidence of postoperative complications between the two groups of patients(P>0.05).Conclusion The implementation of multi-measure combined LLR treatment for patients with liver cancer complicated with cirrhosis and portal hypertension has high clinical value and can effectively improve the rehabilitation quality of patients.It is worthy of clinical promotion and application.关键词
肝癌/肝硬化/高血压/门静脉/腹腔镜/肝切除术Key words
liver cancer/cirrhosis/hypertension/portal vein/laparoscopy/hepatectomy分类
医药卫生引用本文复制引用
成超,贾守洪..多措施联合的腹腔镜肝切除术治疗肝癌合并肝硬化并门静脉高压症的临床应用研究[J].中国内镜杂志,2025,31(12):43-48,6.基金项目
横向课题(No:HXGYKJB20210013) （No:HXGYKJB20210013）
