中国药科大学学报2025，Vol.56Issue(6)：766-773,8.DOI:10.11665/j.issn.1000-5048.2024123001
血管纹上转运蛋白与听力损失关系的研究进展
Research progress on the relationship between transporters in the stria vascularis and hearing loss
摘要
Abstract
Stria vascularis(SV),located in the lateral wall of the cochlea,is a highly vascularized tissue that plays a crucial role in maintaining the homeostasis of endolymph and normal auditory function,with its core function relying on the transporter system distributed within it.These transporters in the SV precisely mediate the transport of ions,nutrients,and metabolites,constituting the cornerstone of the homeostasis of endolymph.Abnormal expression or dysfunction of transporters in the SV can lead to an imbalance in the inner ear microenvironment,which can lead to hearing loss.However,the effects of transporters in SV on hearing loss have not been fully clarified.In this paper,the function and distribution of different types of transporters in SV and their relationship with hearing loss are reviewed,providing a new perspective and prospect for exploring the molecular basis of hearing loss and targeted therapies of transporters in the future.关键词
血管纹/转运蛋白/听力损失/内淋巴稳态Key words
stria vascularis/transporter/hearing loss/homeostasis of endolymph分类
医药卫生引用本文复制引用
申凯迪,郭素菡,张德鹏,王广基,周芳..血管纹上转运蛋白与听力损失关系的研究进展[J].中国药科大学学报,2025,56(6):766-773,8.基金项目
This study was supported by the National Natural Science Foundation of China(No.82274014) 基金项目 国家自然科学基金项目(No.82274014) （No.82274014）
