摘要
Abstract
Objective:To analyze the application effect of Ticagrelor combined with Aspirin in elderly patients with unstable angina pectoris of coronary heart disease(CHD).Method:A total of 86 elderly patients with unstable angina pectoris of CHD who were admitted to the Department of Cardiology of Macheng People's Hospital from January to December 2023 were selected as the research subjects.The patients were divided into the observation group and the control group by the envelope method,with 43 cases in each group.The control group was treated with Aspirin+Clopidogrel,while the observation group was treated with Aspirin+Ticagrelor.The clinical efficacy,symptom-related indicators,cardiac function levels,inflammatory factor levels and quality of life of the two groups were compared.Result:The clinical total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,compared with before treatment,the duration of angina pectoris in both groups was shorter,the frequency of angina pectoris attacks was lower,and which in the observation group were superior to the control group(P<0.05).After treatment,compared with before treatment,the left ventricular ejection fraction(LVEF),stroke volume(SV),and cardiac output(CO)in both groups increased,while IL-6 and TNF-α decreased,moreover,compared with the control group,the above indicators in the observation group were better(P<0.05).After treatment,compared with before treatment,the Seattle angina questionnaire(SAQ)scores of both groups increased,and compared with the control group,those of the observation group were higher(P<0.05).Conclusion:The combined treatment of Ticagrelor and Aspirin for elderly patients with unstable angina pectoris of CHD can effectively improve the therapeutic effect,reduce the severity of angina pectoris,and enhance cardiac function and quality of life.关键词
替格瑞洛/阿司匹林/老年/冠心病心绞痛/生存质量Key words
Ticagrelor/Aspirin/Elderly/Angina pectoris of coronary heart disease/Quality of life
