中国药房2025，Vol.36Issue(24)：3036-3040,5.DOI:10.6039/j.issn.1001-0408.2025.24.04
基于德尔菲法构建结直肠癌治疗药物选择评价指标体系
Construction of evaluation index system for the selection of therapeutic drugs for colorectal carcinoma based on Delphi method
摘要
Abstract
OBJECTIVE To establish an evaluation index system for the selection of therapeutic drugs for colorectal carcinoma,providing a basis for clinical medication decision-making.METHODS A preliminary framework for the evaluation index system for the selection of therapeutic drugs for colorectal carcinoma was constructed through literature research and expert surveys.Using the Delphi method,consultations were conducted with 40 experts engaged in the use and evaluation of antitumor drugs,ultimately forming the evaluation system for selecting therapeutic drugs for colorectal carcinoma.RESULTS The effective recovery rate of questionnaires for both rounds of inquiries was 100%,with the reliability coefficients of 0.82 and 0.85.The Kendall's W coordination coefficients were 0.251 and 0.252(the P values of χ 2 tests were both less than 0.05).The final evaluation system constructed included 6 first-level indicators(safety,efficacy,cost-effectiveness,suitability,innovation,and accessibility)and 29 second-level indicators(such as disease control rate,precise treatment of target diseases,objective remission rate,and whether clinical medication complies with authoritative recommendations).Among these,efficacy and accessibility received high average importance scores(4.60,4.30 points),with"disease control rate"and"precision treatment for target disease"carrying relatively high weights(both were 0.035 2).CONCLUSIONS This study successfully established a drug evaluation index system for the selection of therapeutic drugs for colorectal cancer that aligns with clinical practice.关键词
结直肠癌/药物选择/评价指标体系/德尔菲法Key words
colorectal carcinoma/drug selection/evaluation index system/Delphi method分类
医药卫生引用本文复制引用
唐莲,朱龙驯,丰攀峰..基于德尔菲法构建结直肠癌治疗药物选择评价指标体系[J].中国药房,2025,36(24):3036-3040,5.基金项目
江苏省药学会-奥赛康医院药学科研基金项目(No.A202434) （No.A202434）
