中药材2025，Vol.48Issue(5)：1167-1173,7.DOI:10.13863/j.issn1001-4454.2025.05.017
草麻黄根木脂素类化学成分研究
Lignans from the Roots of Ephedra sinica
摘要
Abstract
Objective:To study the lignans from the roots of Ephedra sinica.Methods:The chemical constituents from the water ex-traction of the roots of Ephedra sinica were isolated and purified by silica gel,Sephadex LH-20,semi-preparative HPLC and other meth-ods,the compounds were identified according to the physiochemical properties and spectral data.Results:Twenty-five lignans were isola-ted from water extraction of the roots of Ephedra sinica and identified as secoisolariciresinol(1),equiselignan F(2),piperphilippinin Ⅵ(3),dihydrocubebin(4),(8S,8′S)-3,3′-dimethoxyligna-4,4′,9,9′-tetraol-9-actate(5),(2R,3R)-bis[(4-hydroxy-3-methoxyphenyl)methy1]-1,4-diacetate(6),matairesinol(7),5-methoxyisolariciresinol(8),isolariciresinol(9),pinoresinol(10),medioresinol(11),epipinoresinol(12),syringaresinol(13),episyringaresinol(14),lariciresinol(15),lariciresinol 3-acetate(16),ciwujiatone(17),san-shodiol(18),dihydrosesamin(19),enythro-geaiacylglycerol-β-O-4′-siapylether(20),bombasin(21),(7S,8R)-ceplignan(22),(7R,8S)-dihydrodehydrodiconiferyl alcohol(23),9′-O-ethyl-dehydrodiconiferyl alcohol(24),sesquipinsapol B(25),respectively.Conclu-sion:Among them,compounds 1,5 to 24 are isolated from Ephedra sinica for the first time.关键词
草麻黄根/提取分离/结构鉴定/木脂素类Key words
The roots of Ephedra sinica Stapf/Extraction and isolation/Structural identification/Lignans分类
医药卫生引用本文复制引用
徐雅桐,杨颖,张博文,李孟,郑晓柯,冯卫生..草麻黄根木脂素类化学成分研究[J].中药材,2025,48(5):1167-1173,7.基金项目
中央引导地方科技发展专项(豫财科[2016]149号) （豫财科[2016]149号）
