中医临床研究2025，Vol.17Issue(28)：102-106,5.DOI:10.3969/j.issn.1674-7860.2025.28.015
基于证素及证型分布规律探讨复发性大肠息肉的"既病防变"策略
Exploring the strategy of"preventing disease from exacerbating"for recurrent colorectal polyps based on the distribution pattern of syndrome elements and syndrome types
摘要
Abstract
Objective:By analyzing the distribution patterns of syndrome elements and syndrome types in patients with recurrent colorectal polyps,the strategy of"preventing disease from exacerbating"for recurrent colorectal polyps was explored.Methods:Relevant clinical information of patients with colorectal polyps who were hospitalized multiple times and undergone colonoscopy examination and treatment in the Affiliated Hospital of Zunyi Medical University were collected to clarify the disease location and pathological syndrome elements,and cluster analysis and factor analysis were performed to obtain the combination pattern of syndrome elements.At the same time,the patients'syndrome type was clarified according to the traditional Chinese medicine(TCM)syndrome type collection scale,and the relationship between the syndrome type and the combination rules of syndrome elements was compared.Results:A total of 10 disease location elements and 15 pathological syndrome elements were extracted,among which the high-frequency disease location syndrome elements were as follows in order:spleen,large intestine,kidney,stomach and liver.The high-frequency pathogenic syndrome elements were as follows in order:dampness,stasis,phlegm,Qi(气)deficiency,Qi stagnation,heatness and Yang(阳)deficiency.The clustering results of high-frequency syndrome elements were divided into four types:kidney,Yang deficiency,cold,Qi deficiency.Stomach,Qi stagnation,liver.Large intestine,heat.Spleen,dampness,phlegm,and blood stasis.There were four factor analysis results as follows in order:spleen,kidney,Qi deficiency,Yang deficiency,cold.Liver,stomach,Qi stagnation.Large intestine,heat.Dampness,phlegm,and blood stasis.The TCM clinical syndrome types from high to low were spleen deficiency with dampness,Yang deficiency with cold coagulation,intestinal dampness and heat,Qi stagnation and blood stasis,liver depression with spleen deficiency,and intestinal dryness and fluid deficiency.Conclusion:TCM syndrome type-based differentiation essentially covers the key points of syndrome differentiation and treatment for recurrent colorectal polyps.Meanwhile,syndrome element-based differentiation can reveal more underlying pathological changes,indicating the organs that likely to be affected and potential shifts in pathogenesis.While conducting treatment based on syndrome types in clinical practice,one can also refer to syndrome element to address multiple syndrome elements such as spleen,kidney,dampness,phlegm,and stasis,which reflects the TCM therapeutic principle of"preventing disease from exacerbating".关键词
复发性大肠息肉/既病防变/证素/证型Key words
Recurrent colorectal polyp/Preventing disease from exacerbating/Syndrome element/Syndrome type分类
医药卫生引用本文复制引用
杜川林,汪媛,秦建平,陈龙开,李云云,王怡如,徐凡..基于证素及证型分布规律探讨复发性大肠息肉的"既病防变"策略[J].中医临床研究,2025,17(28):102-106,5.基金项目
贵州省遵义市科技与大数据局资助科研课题(遵市科合HZ字[2022]364号). （遵市科合HZ字[2022]364号）
