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细胞膜仿生载体用于抗肿瘤治疗的研究进展

吴佳禾 王楠 高建青 林能明

肿瘤防治研究2025,Vol.52Issue(12):973-979,7.
肿瘤防治研究2025,Vol.52Issue(12):973-979,7.DOI:10.3971/j.issn.1000-8578.2025.25.0550

细胞膜仿生载体用于抗肿瘤治疗的研究进展

Advancements in Cell Membrane-Based Biomimetic Carriers for Antitumor Therapy

吴佳禾 1王楠 2高建青 3林能明1

作者信息

  • 1. 310006 杭州,西湖大学医学院附属杭州市第一人民医院临床药学部,浙江省临床肿瘤药理与毒理学研究重点实验室
  • 2. 310006 杭州,西湖大学医学院附属杭州市第一人民医院临床药学部,浙江省临床肿瘤药理与毒理学研究重点实验室||310058 杭州,浙江大学药学院,先进药物递释系统全国重点实验室
  • 3. 310058 杭州,浙江大学药学院,先进药物递释系统全国重点实验室
  • 折叠

摘要

Abstract

Drug delivery technologies are crucial components in drug development,greatly enhancing drug bioavailability and therapeutic efficacy and reducing toxic side effects.Cell membrane-based biomimetic carriers have attracted considerable interest owing to their intrinsic biointeractive capability derived from source cells in vivo.This review summarizes the fundamental properties and functional attributes of cell membrane-based biomimetic carriers from different cellular sources and discusses their advancements in tumor-targeted drug delivery and role in the activation of antitumor immunity.Ultimately,the discussion focuses on the prospects and potential challenges in employing cell membrane-based biomimetic carriers for antitumor treatment.

关键词

细胞膜仿生载体/药物递送/抗肿瘤治疗

Key words

Cell membrane-based bio-mimetic carrier/Drug delivery/Antitu-mor therapy

分类

医药卫生

引用本文复制引用

吴佳禾,王楠,高建青,林能明..细胞膜仿生载体用于抗肿瘤治疗的研究进展[J].肿瘤防治研究,2025,52(12):973-979,7.

基金项目

国家自然科学基金(82304388,82503812) (82304388,82503812)

杭州市医学重点学科建设项目(临床药学2025HZZD02) (临床药学2025HZZD02)

浙江省临床肿瘤药理与毒理学研究重点实验室(2020E10021) National Natural Science Foundation of China(No.82304388,82503812) (2020E10021)

The Construction Fund of Key Medical Disciplines of Hangzhou(No.2025HZZD02) (No.2025HZZD02)

Key Laboratory of Clinical Cancer Pharmacology and Tox-icology Research of Zhejiang Province(No.2020E10021) (No.2020E10021)

肿瘤防治研究

1000-8578

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