肿瘤防治研究2025,Vol.52Issue(12):973-979,7.DOI:10.3971/j.issn.1000-8578.2025.25.0550
细胞膜仿生载体用于抗肿瘤治疗的研究进展
Advancements in Cell Membrane-Based Biomimetic Carriers for Antitumor Therapy
摘要
Abstract
Drug delivery technologies are crucial components in drug development,greatly enhancing drug bioavailability and therapeutic efficacy and reducing toxic side effects.Cell membrane-based biomimetic carriers have attracted considerable interest owing to their intrinsic biointeractive capability derived from source cells in vivo.This review summarizes the fundamental properties and functional attributes of cell membrane-based biomimetic carriers from different cellular sources and discusses their advancements in tumor-targeted drug delivery and role in the activation of antitumor immunity.Ultimately,the discussion focuses on the prospects and potential challenges in employing cell membrane-based biomimetic carriers for antitumor treatment.关键词
细胞膜仿生载体/药物递送/抗肿瘤治疗Key words
Cell membrane-based bio-mimetic carrier/Drug delivery/Antitu-mor therapy分类
医药卫生引用本文复制引用
吴佳禾,王楠,高建青,林能明..细胞膜仿生载体用于抗肿瘤治疗的研究进展[J].肿瘤防治研究,2025,52(12):973-979,7.基金项目
国家自然科学基金(82304388,82503812) (82304388,82503812)
杭州市医学重点学科建设项目(临床药学2025HZZD02) (临床药学2025HZZD02)
浙江省临床肿瘤药理与毒理学研究重点实验室(2020E10021) National Natural Science Foundation of China(No.82304388,82503812) (2020E10021)
The Construction Fund of Key Medical Disciplines of Hangzhou(No.2025HZZD02) (No.2025HZZD02)
Key Laboratory of Clinical Cancer Pharmacology and Tox-icology Research of Zhejiang Province(No.2020E10021) (No.2020E10021)