KRAS G12C突变晚期非小细胞肺癌治疗研究进展
Therapeutic Progress in Advanced KRAS G12C-Mutant Non-Small Cell Lung Cancer
摘要
Abstract
This article elucidates therapeutic approaches for KRAS G12C-mutant advanced non-small cell lung cancer,with focus on global advancements in inhibitor research.It also summarizes clinical evidence on the efficacy of targeted agents in monotherapy and combination therapies,analyzes their clinical advantages and challenges,and explores future directions for novel treatment modalities.关键词
KRAS G12C/非小细胞肺癌/靶向治疗Key words
KRAS G12C/Non-small cell lung cancer/Targeted therapy分类
医药卫生引用本文复制引用
刘义,黄臻,陈露露,宋启斌..KRAS G12C突变晚期非小细胞肺癌治疗研究进展[J].肿瘤防治研究,2025,52(12):1012-1020,9.基金项目
National Natural Science Foundation of China(No.82273094) （No.82273094）
Hubei Provincial Natural Science Foundation General Project(No.2025AFB749) （No.2025AFB749）
The Fundamental Research Funds for the Central Univ-ersities(No.2042025YXB006) （No.2042025YXB006）
Undergraduate Training Programs for Innovation of Wuhan University(No.S202510486411) （No.S202510486411）
2024 Wuhan University School of Medicine Teaching Program(No.2024YB12) （No.2024YB12）
Hubei Province Health Science and Technology Project General Project(No.WJ2025M100) 国家自然科学基金(82273094) （No.WJ2025M100）
湖北省自然科学基金面上项目(2025AFB749) （2025AFB749）
中央高校基本科研业务费专项资金资助(2042025YXB006) （2042025YXB006）
武汉大学大学生创新训练计划项目(S202510486411) （S202510486411）
2024武汉大学医学部教学项目(2024YB12) （2024YB12）
湖北省卫生健康科技项目面上项目(WJ2025M100) （WJ2025M100）
