中国康复2025，Vol.40Issue(12)：721-726,6.DOI:10.3870/zgkf.2025.12.003
基于动作和任务的运动想象对脑卒中患者运动皮层区激活的影响
Effects of movement and task-based motor imagery on motor cortical activation patterns in stroke patients
摘要
Abstract
Objective:To analyze and compare the concentration changes of oxyhemoglobin(HbO2)in the motor cortex and the activation patterns of brain regions in stroke patients during Movement-Based Motor Imagery(MMI)and Task-Based Motor Imagery(TMI)using functional near-infrared spectroscopy(fNIRS).This aims to provide neuroimaging evidence for motor imagery(MI)therapy.Methods:Totally,20 patients with left-sided stroke receiv-ing rehabilitation therapy at Zhejiang Rehabilitation Medical Center between January and December 2022 were con-secutively enrolled.A block design was employed,with participants randomly performing both MMI and TMI tasks.A portable fNIRS device monitored HbO2 concentration changes in the bilateral sensorimotor cortex(SMC),premotor cortex(PMC),and supplementary motor area(SMA).The activation levels(β-values)of these brain re-gions were compared between the two MI states.Results:Totally,20 patients were included in the statistical analy-sis.Based on HbO2 concentration,stroke patients exhibited significant activation in 16 channels during the MMI task and 19 channels during the TMI task.The mean activation β-value in channel 3 was significantly higher during TMI than MMI(T=4.31,P＜0.05).Patients also reported significantly higher visual imagery scores during the TMI task than during MMI(Z=-2.013,P＜0.05).Conclusion:Both MMI and TMI significantly activated the bilateral SMC,PMC,and SMA in stroke patients.Activation during TMI covered a broader range and was stronger in specific regions.The goal-directed task of TMI likely contributed to its higher vividness of imagination.关键词
脑卒中/运动想象/基于任务的运动想象/近红外脑功能成像/氧合血红蛋白/运动皮层区Key words
stroke/motor imagery/task-based motor imagery/functional near-infrared spectroscopy/oxyhemo-globin/motor cortex area分类
医药卫生引用本文复制引用
王佳灵,宋建飞,贾欣宇,陈健尔..基于动作和任务的运动想象对脑卒中患者运动皮层区激活的影响[J].中国康复,2025,40(12):721-726,6.基金项目
浙江省医药卫生科技计划项目(2022KY1049) （2022KY1049）
