中国康复2025，Vol.40Issue(12)：737-741,5.DOI:10.3870/zgkf.2025.12.006
内热针疗法对颈肩肌筋膜疼痛综合征患者线粒体功能影响的研究
Effect of internal heat-type acupuncture needle therapy on mitochondrial function in patients with cervicoshoulder myo-fascial pain syndrome
摘要
Abstract
Objective:To evaluate the analgesic effect of internal heat-type acupuncture needle on patients with cer-vicoshoulder myofascial pain syndrome and to explore the underlying mechanism through which it exerts therapeutic effects.Methods:A total of 100 patients diagnosed with cervicoshoulder myofascial pain syndrome who met the in-clusion criteria were enrolled in the study between December 2021 and December 2023.Participants were randomly divided into two groups-control group and treatment group-using a random number table method.Patients in the control group received myofascial trigger point injections of 0.5％lidocaine,and those in the treatment group under-went internal heat-type acupuncture needle at the myofascial trigger points.Treatments were administered every two days,with 5 sessions comprising one treatment course;a total of two courses were conducted.The Visual Analogue Scale(VAS),Pain Rating Index(PRI),and Present Pain Intensity(PPI)scores were compared between the two groups before and after treatment.Furthermore,the expression levels of mitochondrial transcription factor A(mt-TFA),a key molecule associated with mitochondrial function,were measured in peripheral blood samples collected from all participants pre-and post-treatment.Results:Following treatment,both groups exhibited significant im-provements in VAS,PRI,and PPI scores compared to pre-treatment values(P＜0.05),along with an increase in mtTFA expression levels(P＜0.05).However,the internal heat-type acupuncture needle group demonstrated sig-nificantly reductions in pain scores and more pronounced increases in mtTFA expression compared to the control group(P＜0.05).Therapeutic efficacy was further evaluated using the nimodipine method,revealing a total effec-tive rate of 80％in the lidocaine group and 88％in the internal heat-type acupuncture needle group.These results indicate a statistically significant difference in treatment effectiveness between the two groups(P＜0.05).Conclus-ion:Both lidocaine injection and internal heat-type acu-puncture needle demonstrate favorable clinical efficacy in treating cervicoshoulder myofascial pain syndrome.However,internal heat-type acupuncture needle exhib-its superior therapeutic effects compared to lidocaine in-jection.Moreover,the mechanism of action may in-volve the modulation of mitochondrial dysfunction via upregulation of mtTFA expression.关键词
内热针/肌筋膜疼痛综合征/肌筋膜触发点/线粒体功能Key words
internal heat-type acupuncture needle/myofascial pain syndrome/myofascial trigger point/mitochondrial function分类
医药卫生引用本文复制引用
陈建军,詹力,李石乔,成曦,王泉,常旭升,毛健宇,姚潇麟,杨清胥..内热针疗法对颈肩肌筋膜疼痛综合征患者线粒体功能影响的研究[J].中国康复,2025,40(12):737-741,5.基金项目
云南省科学技术厅中医联合专项-面上项目(202101AZ070001-083) （202101AZ070001-083）
云南省科学技术厅中医联合专项-面上项目(202401AZ070001-045) （202401AZ070001-045）
