中国康复理论与实践2025，Vol.31Issue(12)：1376-1384,9.DOI:10.3969/j.issn.1006-9771.2025.12.002
运动-认知双任务训练对帕金森病患者认知功能的Meta分析
Motor-cognitive dual-task training for cognitive function in patients with Parkinson's disease:a meta-analysis
摘要
Abstract
Objective To explore the effect of motor-cognitive dual-task training on cognitive function in patients with Parkinson's disease(PD). Methods Following the PRISMA guidelines,randomized controlled trials(RCT)evaluating the effect of motor-cogni-tive dual-task training on cognitive function in PD patients were systematically searched in the Cochrane Library,Web of Science,Embase,PubMed,CNKI,Wanfang data,VIP and Chinese Biomedical Literature Database from inception to December 20,2024.The methodological quality of the included studies was assessed using the Co-chrane Handbook for Systematic Reviews of Interventions version 5.1.0 risk-of-bias tool and the PEDro scale.Meta-analysis was conducted using RevMan 5.4,and GRADE approach was applied to evaluate the quality of ev-idence. Result A total of ten studies involving 330 patients were included,with PEDro scores ranging from six to nine.Meta-analysis showed that motor-cognitive dual-task training significantly improved Montreal Cognitive Assessment(MoCA)scores(MD=2.05,95%CI 0.38 to 3.73,P=0.02).There was no difference in Stroop Color and Word Test(SCWT)(reaction time and accuracy),Trail Making Test A(TMT-A)and Trail Making Test B(TMT-B)from the control group(P>0.05).Subgroup analysis indicated that interventions lasting more than three months improved the MoCA scores(MD=3.64,95%CI 3.13 to 4.16,P<0.001).The GRADE rating of evidence was low for MoCA improvement,and moderate for improvements in TMT-A,TMT-B,and Stroop Color-Word Test(reaction time and accuracy). Conclusion Motor-cognitive dual-task training can improve overall cognitive function in patients with PD,as the inter-vention durations more than three months.The effect on visuospatial and executive function requires further in-vestigation.关键词
帕金森病/认知/运动/双任务/认知功能/Meta分析Key words
Parkinson's disease/cognition/motor/dual-task/cognitive function/meta-analysis分类
医药卫生引用本文复制引用
朱艾荣,刘培豪,郭晶,管婷玉,陈玺竹,蔡诗凝,胡雁,张玉侠..运动-认知双任务训练对帕金森病患者认知功能的Meta分析[J].中国康复理论与实践,2025,31(12):1376-1384,9.基金项目
上海市加强公共卫生体系建设三年行动计划(2023-2025年)项目(No.GWVI-11.1-46) Supported by Shanghai Public Health System Construction Three-Year Action Plan(2023-2025)(No.GWVI-11.1-46) （2023-2025年）
