重庆医学2025，Vol.54Issue(12)：2792-2797,6.DOI:10.3969/j.issn.1671-8348.2025.12.012
反应性充血外周压力测定在冠心病患者血管内皮功能评估中的应用效果
Application effect of reactive hyperemia peripheral manometry in the assessment of vascular endothelial function in patients with coronary heart disease
摘要
Abstract
Objective To investigate the correlation between endothelial function assessed by reactive hyperemia-peripheral arterial tonometry(RH-PAT)and coronary heart disease.Methods A retrospective a-nalysis was conducted on the clinical data of 307 patients who were scheduled to undergo coronary angiogra-phy in Department of Cardiology of Beijing Hospital from November 2023 to May 2024.According to the re-sults of coronary angiography,they were divided into the coronary heart disease group(n=257)and the non-coronary heart disease group(n=50).Vascular endothelial function was evaluated using RH-PAT,and the endothelial function status was reflected by the reactive congestion index(RHI).Potential confounding factors were excluded through propensity score matching,and the differences in RHI between the two groups were analyzed.Logistic regression was used to analyze the relationship between gender,age,hypertension,hyperlipi-demia,diabetes,smoking and RHI in patients with coronary heart disease.Results Before propensity score matching,there were statistically significant differences between the two groups in terms of gender,hyperlipi-demia,diabetes,smoking,blood glucose,blood lipids,number of diseased vessels,and Gensini score(P<0.05).After propensity score matching,the only statistically significant difference between the two groups was the number of diseased vessels(P<0.05).Multivariate logistic regression analysis showed that gender and smoking were influencing factors for RHI(P<0.05).Conclusion RH-PAT can be used to determine en-dothelial dysfunction in patients with coronary heart disease,and gender and smoking may be influencing fac-tors for RHI.关键词
内皮功能/内皮功能障碍/动脉粥样硬化/冠心病/无创检测Key words
endothelial function/endothelial dysfunction/atherosclerosis/coronary artery disease/inva-sive detection分类
医药卫生引用本文复制引用
LIU Junmeng,MU Chunfu,MU Xinyue,LAN Ming,LIU Bing,JIA Na..反应性充血外周压力测定在冠心病患者血管内皮功能评估中的应用效果[J].重庆医学,2025,54(12):2792-2797,6.基金项目
中央高水平医院临床科研业务费专项(BJ-2024-165). （BJ-2024-165）
