肝胆胰外科杂志2025，Vol.37Issue(12)：797-801,5.DOI:10.11952/j.issn.1007-1954.2025.12.002
保留十二指肠胰头全切除术的临床应用
Clinical application of duodenum-preserving total pancreatic head resection
摘要
Abstract
Objective To evaluate indications,key technical steps,postoperative outcomes,and complication management of duodenum-preserving total pancreatic head resection(DPPHRt)for benign or borderline lesions of the pancreatic head.Methods A retrospective analysis was conducted on clinical data from 8 patients with benign or borderline pancreatic head lesions who underwent DPPHRt at the First Affiliated Hospital of University of Science and Technology of China,between January 2020 and January 2025.Intraoperative and postoperative parameters were recorded and analyzed,and follow-up was conducted to evaluate recovery.Results All 8 patients successfully underwent the DPPHRt.Pathology included solid pseudopapillary tumor(n=4),serous cystic neoplasm(n=2),mucinous cystic neoplasm(n=1),and intraductal papillary mucinous neoplasm(n=1).Intraoperative frozen sections confirmed diagnoses;7 cases were open and 1 laparoscopic.The median operation time was 432.5(295.0,497.5)min and intraoperative blood loss was 200.0(125.0,200.0)mL,one patient received a transfusion of 1 unit of red blood cells.Postoperative complications occurred in three patients(two grade B postoperative pancreatic fistulas,including one with secondary intra-abdominal infection,and one bile leak),all of whom recovered with conservative management,and no postoperative hemorrhage or delayed gastric emptying occurred.Time to first flatus,time to drain removal,time of postoperative hospitalization were 3.5(2.5,5.0)days,13.5(8.5,21.5)days,23.5(12.5,25.0)days,respectively,and there was no perioperative mortality.With a median follow-up of 863(532,1 151)days,all patients recovered well without perioperative death or late complications.Conclusion As a function-preserving pancreatic operation,the DPPHRt is safe and effective for non-malignant lesions of the pancreatic head.Meticulous intraoperative technique with preservation of key anatomical structures and careful postoperative management are essential for broader clinical adoption.关键词
保留十二指肠胰头全切除术/胰头良性肿瘤/胰头交界性肿瘤/胰瘘/术后并发症Key words
duodenum-preserving/total pancreatic head resection/benign pancreatic head tumor/borderline pancreatic head tumor/pancreatic fistula/postoperative complications分类
医药卫生引用本文复制引用
WANG Gang,ZHOU Meng,XU Shibo,WANG Cheng..保留十二指肠胰头全切除术的临床应用[J].肝胆胰外科杂志,2025,37(12):797-801,5.基金项目
国家自然科学基金青年基金(82203856) （82203856）
2022年安徽省重点研究与开发计划(2022e07020006) （2022e07020006）
中国科学技术大学附属第一医院医疗领先技术引进项目(2023LXJS-05). （2023LXJS-05）
