中医学报2026，Vol.41Issue(1)：7-13,7.DOI:10.16368/j.issn.1674-8999.2026.01.002
动脉粥样硬化相关泛血管疾病的中医病机与治疗策略
Traditional Chinese Medicine Pathogenesis and Contemporary Research Progress in Atherosclerosis-Related Panvascular Diseases
摘要
Abstract
Panvascular diseases are systemic vascular syndromes characterized by atherosclerosis(AS)as the core pathological change.Although panvascular diseases are fundamentally viewed as an overall imbalance of Yin and Yang with the internal generation of Cold E-vil Factor,their pathogenesis is closely related to dysfunctions of the internal Zang and Fu,particularly the Heart,Spleen and Kidney.AS-related panvascular diseases have"Yin-Yang imbalance"as the core pathogenesis,essentially representing an intertwining of Yang deficiency and excess Yin.Insufficient Heart Yang leads to weak blood circulation,Spleen Yang deficiency causes internal genera-tion of Phlegm and Dampness,and Kidney Yang deficiency results in impaired Qi transformation.All of the above lead to the internal presence of Cold.When Cold obstructs the vessels,pathological products such as Phlegm and blood stasis accumulate,and with pro-longed disease development,the vascular pathways are damaged,leading to the onset of some related conditions.Clinically,treatment should follow the principle of"warming Yang to consolidate the root and then harmonizing Yin and Yang",aiming to restore the body's dynamic Yin-Yang balance through a coordinated approach that warms Heart Yang,strengthens Spleen Yang,and supplements Kid-ney Yang.Additionally,treatment should be staged according to the formation phase of atherosclerotic plaques to achieve precise inter-vention.In the early stage,when Phlegm and blood stasis are initially congealed but the vessels are not yet obstructed and symptoms are not pronounced,the treatment focuses on strengthening the Middle Jiao and warming Yang to dissolve Turbidity.In the middle stage,when Phlegm and blood stasis have formed plaques and lumen narrowing is evident,the signs of Phlegm-Dampness and blood stasis are prominent,and treatment should focus on removing stasis,transforming Phlegm,dispersing nodules,and eliminating plaques.In the late stage,when prolonged obstruction by Phlegm-Dampness and blood stasis transforms into pathogenic Heat and Turbidity,and when plaques are prone to rupture,the solution lies in clearing Heat,detoxifying,stabilizing vulnerable plaques and preventing AS progres-sion.关键词
泛血管疾病/动脉粥样硬化/阴阳失衡/寒伏脉络/脏腑失衡/痰瘀互结/免疫稳态/氧化应激/血管内皮功能/肠道微生态Key words
panvascular disease/atherosclerosis/Yin-Yang imbalance/Cold obstructs the vessels/imbalance of Zang and Fu/phlegm and blood stasis intermingling/immune homeostasis/oxidative stress/endothelial function of blood vessels/gut microbiota分类
医药卫生引用本文复制引用
TONG Tong,YANG Yuhan,JIANG Lingyan,WANG Qingqing,WANG Zeqi,YAO Kuiwu..动脉粥样硬化相关泛血管疾病的中医病机与治疗策略[J].中医学报,2026,41(1):7-13,7.基金项目
癌症、心脑血管、呼吸和代谢性疾病防治研究国家科技重大专项项目(四大慢病重大专项)(2024ZD0528300,2024ZD0528304) （四大慢病重大专项）
2024年岐黄学者培养项目(中医药领军人才培养项目){国中医药人教函[2025]182号} （中医药领军人才培养项目）
中国中医科学院眼科医院中央高水平中医医院项目(GSP3-08) （GSP3-08）
