西南医科大学学报2026，Vol.49Issue(1)：68-72,5.DOI:10.3969/j.issn.2096-3351.2026.01.012
微创甲状腺手术后甲状腺乳头状癌患者甲状旁腺功能恢复的时间及相关影响因素
Recovery Time of Parathyroid Function and Its Influencing Factors in Patients with Papillary Thyroid Cancer after Minimally Invasive Thyroidectomy
摘要
Abstract
Objective This study aimed to investigate the effect of minimally invasive thyroid surgery on postoperative parathy-roid function recovery in patients with The First Affiliated Hospital of Xinxing Medical Collega(PTC),determining the recovery time and related influencing factors.Methods This study is a cohort study.Clinical data were collected from 110 PTC patients who under-went surgery at The First Affiliated Hospital of Xinxiang Medical College from January 2023 to January 2024,including 55 patients who received minimally invasive surgery and 55 who received traditional open surgery.The data included preoperative thyroid and para-thyroid function indicators,intraoperative parathyroid identification and protection,operative time,postoperative serum calcium and parathyroid hormone(PTH)levels,recovery time of parathyroid function,postoperative complications(e.g.,hypocalcemia),length of hospital stay,and postoperative pain scores.Multivariate Cox regression analysis was used to identify factors affecting parathyroid func-tion recovery,and postoperative indicators were compared between groups.Results The recovery time of parathyroid function was sig-nificantly shorter in the minimally invasive group than in the conventional surgery group[median recovery time:10(8～12)days vs.17(15～21)days,P<0.001].Postoperative serum calcium and PTH levels at 24 and 72 hours were significantly higher in the mini-mally invasive group compared to the traditional group(P<0.001),with a lower incidence of hypocalcemia(15.8%vs.32.5%,P=0.005).Multivariate Cox regression analysis showed that the type of surgery(HR=0.55,95%CI:0.33～0.91,P=0.021),intraop-erative parathyroid protection(HR=0.58,95%CI:0.35～0.95,P=0.037),early postoperative serum calcium levels(HR=1.32,95%CI:1.10～1.60,P=0.002),and operative time(HR=1.12,95%CI:1.05～1.20,P=0.001)were independent factors affect-ing parathyroid function recovery.Additionally,the minimally invasive group had a significantly shorter hospital stay(5.2 vs.7.8 days,P<0.001)and lower pain scores on postoperative days 1 and 3(P<0.001)compared to the traditional group.Conclusions Mini-mally invasive thyroid surgery demonstrates significant advantages in promoting parathyroid function recovery in PTC patients,reduc-ing recovery time and hypocalcemia incidence while shortening hospital stay and minimizing postoperative pain.The type of surgery and intraoperative parathyroid protection are key factors influencing recovery.关键词
甲状腺乳头状癌/微创手术/甲状旁腺功能/恢复时间/影响因素Key words
Papillary thyroid carcinoma/Minimally invasive surgery/Parathyroid function/Recovery time/Influencing factor分类
医药卫生引用本文复制引用
GAO Yanxin,WANG Lei,SONG Pengfei,QIN Shuang,XUE HuiChao..微创甲状腺手术后甲状腺乳头状癌患者甲状旁腺功能恢复的时间及相关影响因素[J].西南医科大学学报,2026,49(1):68-72,5.基金项目
河南省高等学校重点科研项目(21A320021) （21A320021）
