内科理论与实践2025,Vol.20Issue(5):376-380,5.DOI:10.16138/j.1673-6087.2025.05.05
住院肝硬化患者营养风险评估与临床转归的相关性研究
Study on correlation between nutritional risk assessment and clinical outcome in hospitalized patients with cirrhosis
摘要
Abstract
Objective To evaluate the nutritional risk in hospitalized patients with cirrhosis and explore the relationship between nutritional risk and clinical prognosis.Methods A total of 401 patients with cirrhosis admitted to the infectious diseases department of a grade-Ⅲ hospital in Shanghai from June 2020 to June 2022 were selected as study subjects.The nutritional risk assessment was performed using the Royal Free Hospital-nutrition prioritizing tool(RFH-NPT),and the general information,disease status,laboratory indicators,and clinical prognosis of cirrhosis patients with different nutritional risks were compared.Results In 401 patients,86(21.45%)cases had moderate nutritional risk,and 122(30.42%)cases had high nutritional risk.There were differences in etiological classification,model for end-stage liver disease(MELD)score,Child-Pugh grade,abdominal water volume and laboratory indexes of serum albumin,prealbumin,triglyceride and hemoglobin among patients with different nutritional risks(P<0.05).With the increase of nutritional risk grade,the incidence of infection,upper gastrointestinal bleeding and electrolyte disturbance increased,and the score of activity of daily living decreased(P<0.05).Conclusions Cirrhosis patients with moderate to high nutritional risk have severer liver function impairment,high complication rate and poor clinical prognosis compared to those at lower risk.关键词
肝硬化/营养风险/临床转归/RFH-NPTKey words
Liver cirrhosis/Nutritional risk/Clinical outcome/RFH-NPT分类
医药卫生引用本文复制引用
WANG Lin,XIANG Xiaogang,LI Li,QIAN Zhuping..住院肝硬化患者营养风险评估与临床转归的相关性研究[J].内科理论与实践,2025,20(5):376-380,5.基金项目
上海申康医院发展中心促进市级医院临床技能与临床创新三年行动计划(SHDC2022CRS002A) (SHDC2022CRS002A)
上海交通大学医学院护理学科人才培养计划(SJTUHLXK2024) (SJTUHLXK2024)
上海交通大学医学院附属瑞金医院护理科研基金项目[RJKH(Z)-2024-008] (Z)