内科理论与实践2025，Vol.20Issue(5)：393-398,6.DOI:10.16138/j.1673-6087.2025.05.09
奥沙利铂致周围神经病变的研究进展
Research progress on oxaliplatin-induced peripheral neuropathy
摘要
Abstract
Oxaliplatin-induced peripheral neuropathy(OIPN)is a common dose-limiting toxic reaction in chemotherapy for gastrointestinal malignancies such as colorectal and gastric cancers,is characterized by sensory abnormalities and pain that substantially impair treatment efficacy and quality of life.This article provides a systematic review of the pathogenesis,diagnostic criteria,contributing factors,and therapeutic strategies of OIPN,aiming to raise clinician's attention to OIPN and provide a reference for future clinical management in oncological practice.关键词
周围神经病变/奥沙利铂/发病机制/症状管理Key words
Peripheral neuropathy/Oxaliplatin/Pathogenesis/Symptom management分类
医药卫生引用本文复制引用
ZHANG Yi,QIU Xiaoxia..奥沙利铂致周围神经病变的研究进展[J].内科理论与实践,2025,20(5):393-398,6.基金项目
江苏省研究生科研与实践创新计划项目(SJCX25_1535) （SJCX25_1535）
