世界科学技术-中医药现代化2025，Vol.27Issue(12)：3660-3666,7.DOI:10.11842/wst.20250804004
基于肝风内动理论探讨针灸治疗帕金森病的作用机制
Exploring the Mechanism of Acupuncture in Treating Parkinson's Disease Based on the Theory of Internal Stirring of Liver Wind
摘要
Abstract
Parkinson's disease(PD)exhibits a complex pathogenesis involving both degeneration of the central nervous system and dysfunction of peripheral organs related to the TCM concept of"internal stirring of liver wind",characterized by multisystem functional disturbances.The Traditional Chinese Medicine(TCM)theory of"internal stirring of liver wind"provides a systematic explanation for its etiology and pathogenesis.Centering on this core pathogenesis,and first elucidating its theoretical connotation and its deep connection with acupuncture theory,this review integrates modern medical research on hepatic metabolism,detoxification,and inflammatory responses to explore the multidimensional mechanisms by acupuncture,based on the principle of"regulating the liver to extinguish wind",in treating PD.Furthermore,the article outlines the application prospects of acupuncture in identifying novel therapeutic targets and facilitating clinical translation.It proposes an integrated therapeutic strategy focusing on the"liver"as a key intervention point,offering novel insights for the precise management of PD.关键词
帕金森病/肝风内动/针灸/作用机制/肝脏Key words
Parkinson's disease/Internal stirring of liver wind/Acupuncture/Mechanism of action/Liver分类
医药卫生引用本文复制引用
ZHANG Yun,LI Wei,XU Shifen,MI Yiqun,ZHANG Jie,XU Jun..基于肝风内动理论探讨针灸治疗帕金森病的作用机制[J].世界科学技术-中医药现代化,2025,27(12):3660-3666,7.基金项目
上海市卫生健康委员会(ZY(2025-2027)-3-2-1):上海市进一步加快中医药传承创新发展三年行动计划(2025年-2027年)海派中医非药物疗法推广体系建设项目,负责人:宓轶群、张洁. （ZY(2025-2027）
