上海预防医学2025，Vol.37Issue(10)：835-841,7.DOI:10.19428/j.cnki.sjpm.2025.250208
2022年上海市社区精神分裂症患者心血管疾病共病现状及影响因素
Comorbidity status of cardiovascular diseases and its influencing factors in community-based schizophrenia patients in Shanghai,2022
摘要
Abstract
[Objective]To investigate the prevalence of cardiovascular diseases and their influencing factors in community-based schizophrenia patients in Shanghai,and to provide a scientific basis for the early identification and prevention of cardiovascular disease in this population.[Methods]Based on the Shanghai community cohort with severe mental disorders in 2022,a total of 3 954 community-based schizophrenia patients were identified and included in this study through a stratified cluster sampling method.Basic information and relevant clinical data(including metabolic index data)were collected through questionnaire survey,physical examination and laboratory testing.Univariate analyses were performed using the chi-square tests,and multivariate logistic regression analyses were employed to identify influencing factors of comorbid cardiovascular diseases.[Results]A total of 3 954 community-based schizophrenia patients were included,of which a total of 1 237(31.28%)patients had comorbid cardiovascular diseases.Multivariate logistic regression analyses showed that age 60 years old or above(OR=5.524,95%CI:3.716-8.214),smoking behavior(OR=1.328,95%CI:1.042-1.692),overweight(OR=1.900,95%CI:1.046-3.451)or obesity(OR=2.678,95%CI:1.439-4.985),elevated blood pressure(OR=1.546,95%CI:1.294-1.846),abnormal fasting blood glucose(OR=1.552,95%CI:1.322-1.823)and high-density lipoprotein cholesterol abnormalities(OR=1.283,95%CI:1.025-1.606)were positively associated with the risk of comorbid cardiovascular diseases in patients with schizophrenia,while educational attainment of college/bachelor's degree or above(OR=0.640,95%CI:0.450-0.910)and being unmarried(OR=0.552,95%CI:0.457-0.667)were negatively associated with the risk of cardiovascular diseases comorbidity.[Conclusion]Advanced age,unhealthy behaviors and lifestyles,as well as abnormalities in blood pressure,blood glucose,and blood lipids,could all increase the risk of comorbid cardiovascular diseases in community schizophrenia patients.It is suggested to strengthen the monitoring and management of these risk factors in this population in the future,so as to achieve early detection,early diagnosis and early intervention of cardiovascular diseases.关键词
社区/精神分裂症/心血管疾病/影响因素Key words
community/schizophrenia/cardiovascular disease/influencing factor分类
医药卫生引用本文复制引用
YANG Chenyao,ZHANG Weibo,LIU Yanli,WANG Xiaolan,ZHU Yi,WANG Na,JIANG Yihua,WANG Lina,CAI Jun..2022年上海市社区精神分裂症患者心血管疾病共病现状及影响因素[J].上海预防医学,2025,37(10):835-841,7.基金项目
上海市加强公共卫生体系建设三年行动计划学科带头人项目(GWVI-11.2-XD25) （GWVI-11.2-XD25）
上海交通大学文科青年人才培育计划项目(2023QN038) （2023QN038）
上海交通大学医学院科技创新项目(WK2118) （WK2118）
上海市"医苑新星"青年医学人才培养计划(沪卫人事[2022]65号) （沪卫人事[2022]65号）
上海市精神卫生中心院级课题(2023-YJ06) （2023-YJ06）
