畜牧兽医学报2025，Vol.56Issue(12)：5998-6012,15.DOI:10.11843/j.issn.0366-6964.2025.12.006
植物源性黄酮类化合物介导微生物保护肠道屏障的机制
Mechanisms of Plant-derived Flavonoids Mediating Microbial Protection of the Intestinal Barrier
摘要
Abstract
Flavonoids are a class of active ingredients derived from natural plants,which has ex-cellent pharmacological effects such as antiox idant,anti-inflammatory,reducing oxidative stress,improving the structure of intestinal flora,protecting intestinal mucosa,regulating im-munity and promoting growth.This paper provides a systematic review of the role of flavonoids in animal intestinal health and barrier protection,briefly describes their unique physicochemical properties,summarises their digestive,absorptive and metabolic pathways in living organisms,focuses on the interactions between flavonoids and gut microorganisms,and provides insight into how flavonoids can influence the physiological function of the intestinal barrier by mediating the intestinal microbiota and generating key metabolites,such as short-chain fatty acids,bile acids and their receptors and tryptophan and other key metabolites to influence the physiological func-tion of the intestinal barrier.The aim is to lay a solid theoretical foundation for the development and utilization of plant-derived flavonoids in animal feeding and production practices,especially in the study of intestinal health in young animals.关键词
黄酮类化合物/肠道屏障/肠道微生物区系/短链脂肪酸/胆汁酸/色氨酸Key words
flavonoids/intestinal barrier/gut microflora/short-chain fatty acids/bile acids/tryp-tophan分类
农业科技引用本文复制引用
WANG Yushan,LIU Wangjing..植物源性黄酮类化合物介导微生物保护肠道屏障的机制[J].畜牧兽医学报,2025,56(12):5998-6012,15.基金项目
甘肃农业大学-青年导师扶持计划(GAU-QDFC-2024-03) （GAU-QDFC-2024-03）
国家自然科学基金项目(32402789 （）
32260846) （）
甘肃省2025年重大科技项目(25ZDNA008) （25ZDNA008）
甘肃省教育厅产业支撑计划项目(2024CYZC-36) （2024CYZC-36）
甘肃农业大学学科团队项目(GAU-XKTD-2022-22) （GAU-XKTD-2022-22）
国家肉羊产业技术体系(CARS-38) （CARS-38）
