现代中西医结合杂志2025，Vol.34Issue(21)：2934-2940,2947,8.DOI:10.3969/j.issn.1008-8849.2025.21.002
基于影像学及有限元探讨中医体质对股骨头坏死患者股骨头力学承载的影响
Influence of traditional Chinese medicine constitution on the mechanical bearing capacity of femoral head in patients with femoral head necrosis based on imaging and finite element analysis
摘要
Abstract
Objective It is to explore the mechanical bearing capacity of femoral head in femoral head necrosis patients with different traditional Chinese medicine constitutions.Methods Twenty-four patients with femoral head necrosis at Stein-berg stageⅡclassified as Yang deficiency,damp-heat,or blood stasis constitutions and enroll 9 patients with normal femo-ral heads,who visited the Orthopedics Outpatient Department of Guang'anmen Hospital of China Academy of Chinese Med-ical Sciences from January 2022 to January 2024 were enrolled by a retrospective analysis.There were 7 patients(10 hips)in the Yang deficiency group,9 patients(10 hips)in the damp-heat group,8 patients(10 hips)in the blood stasis group,and 9 patients(15 hips)in the normal group.The mean CT densities at the middle plane of coronal position and maximum necrosis plane,along with mechanical parameters(maximum total displacement,maximum displacement in the Z-direc-tion,maximum equivalent stress,and failure coefficient)in finite element analysis were compared among all groups.Re-sults There were significant differences in the mean CT density values at the middle plane of coronal position and maximum necrosis plane(F=11.693,P<0.001;F=9.864,P<0.001),maximum equivalent stress(F=5.305,P=0.003),and failure coefficient(χ2=28.486,P<0.001)among the four groups,but there were no significant differences in the maximum total displacement(χ2=2.984,P=0.394)and maximum displacement in the Z-direction(χ2=2.973,P=0.396)among the four groups.The mean CT density values at the middle plane of coronal position and maximum necrosis plane were significantly higher in all femoral head necrosis groups of different constitutions than those in the normal group(all P<0.05),the mean CT density value at the maximum necrosis plane was significantly higher in the blood stasis con-stitution group than that in the Yang deficiency constitution group(P<0.05);the maximum equivalent stresses were sig-nificantly higher in both the blood stasis constitution group and Yang deficiency constitution group than than in the normal group(both P<0.05);the failure coefficient in the Yang deficiency constitution group was significantly higher than those in the blood stasis constitution group,damp-heat constitution group and normal group(all P<0.05),while the failure co-efficient in the blood stasis constitution group was significantly lower than that in the normal group(P<0.05).Conclu-sion There are differences in the mechanical distribution and bearing capacity of femoral head among femoral head necrosis patients with different traditional Chinese medicine constitutions.Patients with blood stasis constitution have higher mechan-ical strength of femoral head,those with Yang deficiency constitution have reduced load-bearing capacity of trabecular bone which prone to collapse,thereby timely constitutional adjustment should be administered to prevent femoral head collapse.关键词
股骨头坏死/中医体质/力学分析/影像学/有限元Key words
femoral head necrosis/traditional Chinese medicine constitution/mechanical analysis/imaging/finite el-ement analysis分类
医药卫生引用本文复制引用
YU Tong,XIE Limin,SHI Shan,TAN Wenjuan,HAO Zhixiu,ZHANG Zhihai,ZHOU You,LI Xin,ZHANG Zhennan..基于影像学及有限元探讨中医体质对股骨头坏死患者股骨头力学承载的影响[J].现代中西医结合杂志,2025,34(21):2934-2940,2947,8.基金项目
中国中医科学院科技创新工程项目(C12021A03320) （C12021A03320）
中央高水平中医医院临床研究和成果转化能力提升项目(HLCMHPP20230121) （HLCMHPP20230121）
中国中医科学院广安门医院科研基金课题(2018S413) （2018S413）
