眼科学报2025，Vol.40Issue(11)：885-892,8.DOI:10.12419/24082105
2017-2023年眼科患者术前四项感染指标的结果分析
Analysis of four blood-borne pathogens in ophthalmic patients from 2017 to 2023
摘要
Abstract
Objective:To understand the infection status of four blood-borne pathogens among ophthalmology patients in South China and the distribution of positive patients across different eye diseases.Methods:A retrospective analysis of data from outpatient and inpatient or surgical ophthalmic patients who underwent screening for hepatitis B surface antigen(HBsAg),hepatitis C virus antibody(anti-HCV),treponema pallidum antibody(anti-TP)and human immunodeficiency virus antibody(anti-HIV)at Zhongshan Ophthalmic Center of Sun Yat-sen University from January 2017 to December 2023.The positivity rates of these markers were recorded and analyzed.Results:A total of 253246 patients were included in the study,with positivity rates for HBsAg,anti-HCV,anti-TP,and anti-HIV at 9.00%,0.45%,1.55%and 0.13%,respectively.Among these,686 patients tested positive for two or more markers,with the highest co-positivity observed for HBsAg and anti-HCV(57.29%),followed by anti-HIV and anti-TP(15.74%).The positivity rate of HBsAg showed a yearly decline,while the rates for anti-HCV,anti-HIV,and anti-TP remained relatively stable from 2017 to 2023.Males had significantly higher positivity rates for HBsAg,anti-HCV,anti-TP,and anti-HIV compared to females(P<0.001).Significant differences in positivity rates for these markers were also observed across different age groups(P<0.001).In patients with positive HBsAg,anti-HCV,and anti-TP,the proportion of cases with lens diseases were the highest,at 36.72%,39.12%,and 46.97%,respectively.Vitreoretinal diseases followed,with proportions of 22.52%,19.65%,and 19.69%,respectively.Among patients with positive anti-HIV,the proportion of cases with vitreoretinal diseases was the highest,at 42.99%,followed by lens diseases at 26.17%,and uveitis at 8.72%.Conclusions:This study reveals the infection status of four blood-borne pathogens in ophthalmology patients and the distribution of infected patients across different eye diseases,which is significant for assessing the risks of ophthalmic surgery and formulating infection control measures.关键词
眼科/乙型肝炎表面抗原/丙型肝炎病毒抗体/梅毒螺旋体抗体/人类免疫缺陷病毒抗体/阳性率Key words
ophthalmic/hepatitis B virus surface antigen/hepatitis virus antibody/treponema pallidum specific antibody/human immunodeficiency virus antibody/positivity rate分类
医药卫生引用本文复制引用
LIU Qinghua,LIU Sihao,LIAO Jingyu,WU Kaili,DUAN Fang..2017-2023年眼科患者术前四项感染指标的结果分析[J].眼科学报,2025,40(11):885-892,8.基金项目
广东省自然科学基金(2020A1515011364).Th is work was supported by the Natural Science Foundation of Guangdong Province(2020A1515011364). （2020A1515011364）
