医学新知2025，Vol.35Issue(12)：1421-1429,中插3-中插5,12.DOI:10.12173/j.issn.1004-5511.202505030
饮食质量与肌少症性肥胖的关联研究:基于NHANES数据库
Association between dietary quality and sarcopenic obesity:based on the NHANES database
摘要
Abstract
Objective To explore the association between dietary quality and sarcopenic obesity(SO).Methods Based on data from the National Health and Nutrition Examination Survey(NHANES)in the United States from 2011 to 2018,participants in four survey cycles were selected as the study subjects.Weighted multivariate Logistic regression analysis was used to explore the association and interaction between Healthy Eating Index 2020(HEI-2020)and SO,and the mediating effects of inflammation,metabolism,and nutritional status on the relationship between HEI-2020 and SO were analyzed.Results A total of 8,602 participants were included,of whom 504 had SO,with a weighted prevalence of approximately 5.33%,The SO group had lower HEI-2020 scores.Multivariate Logistic regression analysis showed that,after adjusting for age,sex,lifestyle,related comorbidities,and energy intake,compared with low HEI-2020 scores,medium HEI-2020 scores[OR=0.73,95%CI(0.54,0.99)]and high HEI-2020 scores[OR=0.50,95%CI(0.35,0.72)]were negatively correlated with SO.Subgroup analysis showed that,except for low-income groups and those with sedentary time≥8 hours,high HEI-2020 scores were negatively correlated with SO.No interaction was found between age,sex,education level,income level,or sedentary time on the association between HEI-2020 and SO.Mediation analysis showed that systemic inflammatory response index(SIRI),glycated hemoglobin,non-HDL cholesterol to HDL cholesterol ratio(NHHR),albumin,and plasma vitamin D negatively mediated the relationship between HEI-2020 and SO.Conclusion Dietary quality is negatively correlated with SO.HEI-2020 can affect SO through the mediating effects of SIRI,glycated hemoglobin,NHHR,albumin,and plasma vitamin D.We should strengthen dietary health education,improve the dietary quality of residents,and promote healthy aging.关键词
饮食质量/肌少症性肥胖/健康饮食指数/中介分析Key words
Dietary quality/Sarcopenic obesity/Healthy eating index/Mediation analysis分类
医药卫生引用本文复制引用
FENG Yun,GUO Jiankui,GONG Jie,ZHOU Ziqi,ZHANG Yuying,LIU Yuan..饮食质量与肌少症性肥胖的关联研究:基于NHANES数据库[J].医学新知,2025,35(12):1421-1429,中插3-中插5,12.基金项目
国家重点研发计划"老年人群营养健康食品创制和产业化示范"专项(2023YFF1104405) （2023YFF1104405）
广东省重点领域研发计划(2019B020213002) （2019B020213002）
