医学新知2025，Vol.35Issue(12)：1430-1437,8.DOI:10.12173/j.issn.1004-5511.202502099
1990-2021年中国新生儿黄疸的疾病负担分析
Analysis of the disease burden of neonatal jaundice in China from 1990 to 2021
摘要
Abstract
Objective This study analyzed the burden and changing trends of neonatal jaundice(NNJ)in China from 1990 to 2021.Methods Data on the burden of NNJ in China from 1990 to 2021 were collected from the 2021 Global Burden of Disease Study database.Descriptive analysis was performed using indicators such as prevalence,mortality rate,and disability-adjusted life years(DALY)rate.Joinpoint software was used to calculate the average annual percentage change(AAPC)and 95%confidence interval(CI)of the prevalence,mortality rate,and DALY rate,to analyze the temporal trends.Results In 2021,the prevalence,mortality rate,and DALY rate of NNJ in China were 60.17 per 100,000 people,42.06 per 100,000 people,and 3,804.15 per 100,000 person-years.From 1990 to 2021,the prevalence,mortality rate,and DALY rate of NNJ in China all showed a downward trend,with AAPCs of[-1.57%,95%CI(-1.62%,-1.53%)],[-7.01%,95%CI(-7.26%,-6.77%)],and[-7.00%,95%CI(-7.24%,-6.76%)],respectively.In 2021,male infants had higher NNJ prevalence,mortality rate,and DALY rate than female infants;in terms of age,infants aged 0～6 days had higher mortality and DALY rates than infants aged 7～27 days,but there was no significant difference in prevalence.There were significant global inequalities in the burden of NNJ across regions with different Socio-demographic Index(SDI)levels.Low-SDI regions bear the heaviest burden and show the slowest improvement,while China is at an intermediate level.Conclusion The prevalence,mortality rate,and DALY rate of NNJ in China showed a downward trend.The disease burden was higher in male infants than in female infants,and higher in newborns aged 0～6 days than in newborns aged 7～27 days.关键词
新生儿黄疸/疾病负担/患病率/死亡率/DALY率Key words
Neonatal jaundice/Disease burden/Prevalence/Mortality rate/DALY rate分类
医药卫生引用本文复制引用
LI Jiali,MA You,HUANG Zirui,CHENG Yan..1990-2021年中国新生儿黄疸的疾病负担分析[J].医学新知,2025,35(12):1430-1437,8.基金项目
安徽医科大学学科建设项目(9101128801) （9101128801）
