中国输血杂志2025，Vol.38Issue(12)：1673-1677,5.DOI:10.13303/j.cjbt.issn.1004-549x.2025.12.004
江西省献血者人群弓形虫血清流行病学特征分析
The seroepidemiological characteristics of Toxoplasma gondii infection among blood donors in Jiangxi Province
摘要
Abstract
Objective To investigate the current status of Toxoplasma gondii(T.gondii)infection among blood donors in Jiangxi Province,thereby providing scientific evidence for ensuring blood transfusion safety.Methods Serum samples from 1 529 blood donors were tested for T.gondii IgG and IgM antibodies using enzyme-linked immunosorbent assay(ELISA).Positive samples were further analyzed by B1 gene PCR testing and Giemsa staining microscopy.Risk factor data were collected via telephone follow-up.Infection rate differences were analyzed using x2 tests.Results The overall T.gondii infection rate among blood donors was 3.92％(60/1 529),with IgG positivity being predominant(3.86％)and IgM positivity at 0.20％.All antibody-positive samples tested negative for T.gondii DNA.Blood group AB donors had the high-est infection rate(7.00％),whereas group O donors had the lowest rate(2.47％),with a statistically significant difference(x2=8.27,P＜0.05).The infection rate in the 46-55 age group was higher than that in the 18-25 age group,x2=4 237.75,P＜0.05.No significant differences were observed across subgroups stratified by sex,occupation,or education level.Multivariate analysis identified cat/dog ownership(x2=28.23,P＜0.05),and frequent consumption of cold dishes(x2=4.09,P＜0.05)as key risk factors.Conclusion In Jiangxi province,T.gondii infection among blood donors is pre-dominantly characterized by past infection,with higher infection rates observed in blood type AB donors and those aged 46-55.The main risk factors include contact with cats/dogs as pets and frequent consumption of cold dishes.It is recommended to disseminate health knowledge on toxoplasmosis prevention in communities and schools to reduce the transfusion transmis-sion risk.关键词
献血者/弓形虫感染/输血残余风险Key words
blood donors/Toxoplasma gondii infection/residual transfusion risk分类
医药卫生引用本文复制引用
ZHUANG Yanglin,GUO Xinyu,WANG Fang,CHEN Dan..江西省献血者人群弓形虫血清流行病学特征分析[J].中国输血杂志,2025,38(12):1673-1677,5.基金项目
江西省卫生健康委科技计划(202410513) （202410513）
