中国临床医学影像杂志2025，Vol.36Issue(12)：837-841,5.DOI:10.12117/jccmi.2025.12.001
经眶超声多参数评估颅内压升高患者的临床价值研究
A study on the clinical value of transorbital ultrasound multiparameters in evaluating patients with increased intracranial pressure
摘要
Abstract
Objective:To assess the feasibility of using transorbital ultrasound multiparameter evaluation for detecting and evaluating increased intracranial pressure(ICP),and to construct a predictive model for rapid and accurate clinical assessment.Methods:We prospectively selected 136 patients from the neurology department,scheduled for lumbar puncture.Before the procedure,we measured optic nerve ultrasound parameters,including optic nerve sheath diameter(ONSD),ONSD to eyeball transverse diameter ratio(ONSD/ETD),peak systolic velocity(PSV),end-diastolic velocity(EDV),and resistance index(RI)of the central retinal artery.Based on lumbar puncture results,patients were divided into increased ICP and ICP normal groups.We analyzed the correlation between parameters and ICP,and the diagnostic consistency of each parameter.ROC curves were used to identify optimal thresholds,and multivariate binary Logistic regression was applied to construct a predictive model for ICP elevation.Results:ONSD,ONSD/ETD,and RI were significantly higher in the increased ICP group,while PSV and EDV were lower(P<0.001).ONSD,ONSD/ETD,and RI showed positive correlations with ICP,while PSV and EDV showed negative correla-tions(P<0.001).The consistency between parameters and lumbar puncture pressure was significant(P<0.001).A multimodal pre dictive model was developed with the formula:Logit(P)=1.94×ONSD-84.6×ONSD/ETD+0.79×PSV-13.8×RI+11.05.Conclusions:Transorbital ultrasound provides a non-invasive,rapid,and accurate method for increased ICP assessment.A multiparameter ap-proach offers higher diagnostic efficacy than single parameters and may become a key strategy for non-invasive ICP monitoring.关键词
颅内高压/超声检查Key words
Intracranial Hypertension/Ultrasonography分类
医药卫生引用本文复制引用
YU Lan-lan,WANG Xing-heng,GU Peng,YANG Fei,ZOU Yuan,REN Bo,YUAN Hong-mei,HE Peng..经眶超声多参数评估颅内压升高患者的临床价值研究[J].中国临床医学影像杂志,2025,36(12):837-841,5.基金项目
教育部产学合作协同育人项目(250505236300920) （250505236300920）
四川省自然科学基金(24NSFSC7642) （24NSFSC7642）
南充市社科联川北健康人文研究专项课题(NC25CB68) （NC25CB68）
川北医学院校级科研项目(CXSY24-06、CBY23-QDA29) （CXSY24-06、CBY23-QDA29）
川北医学院附属医院院级科研项目(2022LC022、210930、2023-2GC013). （2022LC022、210930、2023-2GC013）
