中国药物经济学2025，Vol.20Issue(12)：20-23,4.DOI:10.12010/j.issn.1673-5846.2025.12.004
基于倾向性评分匹配法比较不同厂家生产的美罗培南治疗革兰氏阴性菌感染的有效性及经济学
Comparative Effectiveness and Economy of Meropenem Produced from Different Manufacturers in Treating Gram-negative Bacterial Infections based on the Propensity Score Matching Method
ZHUO Ma-Ceng 1WU Ya-Jing 1XIN Ya-Wen 1ZHAO Yuan-Jing 1LI Qing 1LIU Jin-Ling 1SHI Yong-Lan 1WANG Ya-Feng1
作者信息
- 1. Department of Pharmacy,Qinghai Provincial People's Hospital,Xining 810000,China
- 折叠
摘要
Abstract
Objective To explore the efficacy and economy of meropenem produced by different manufacturers in the treatment of Gram-negative bacterial infections.Methods A total of 824 patients who were admitted to Qinghai Provincial People's Hospital and used meropenem from January 2021 to July 2022 were selected and divided into the provincial procurement group,the stone pharmaceutical group and the Meiping group according to different drug manufacturers.After propensity score matching,the incremental cost-effectiveness ratio(ICER)of meropenem produced by different manufacturers was compared,and a sensitivity analysis was conducted.Results There was no significant difference in the effective rate among the three groups of drugs.The provincial procurement group had the lowest cost,so it was the most economical.Meiping has the highest cost and is not an economically viable solution.The results of the sensitivity analysis were basically consistent with those of the ICER analysis,indicating that the results of the ICER analysis were relatively reliable.Conclusion The provincial collection of meropenem for the treatment of Gram-negative bacterial infections has more cost-effectiveness advantages.关键词
美罗培南/革兰氏阴性菌/倾向性评分法/成本-效果比/增量成本-效果比Key words
Meropenem/Gram-negative bacteria/Tendency scoring method/Cost-effectiveness ratio/Incremental cost-effectiveness ratio分类
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ZHUO Ma-Ceng,WU Ya-Jing,XIN Ya-Wen,ZHAO Yuan-Jing,LI Qing,LIU Jin-Ling,SHI Yong-Lan,WANG Ya-Feng..基于倾向性评分匹配法比较不同厂家生产的美罗培南治疗革兰氏阴性菌感染的有效性及经济学[J].中国药物经济学,2025,20(12):20-23,4.
