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基于安德森模型的高血压患者服药依从性影响因素的路径分析

ZHANG Meizhu ZHENG Jinfeng SU Shuang ZHANG Ruili ZHANG Jing

中国医院用药评价与分析2025,Vol.25Issue(12):1437-1440,4.
中国医院用药评价与分析2025,Vol.25Issue(12):1437-1440,4.DOI:10.14009/j.issn.1672-2124.2025.12.005

基于安德森模型的高血压患者服药依从性影响因素的路径分析

Path Analysis on Influencing Factors of Medication Compliance in Hypertensive Patients Based on Anderson Model

ZHANG Meizhu 1ZHENG Jinfeng 1SU Shuang 1ZHANG Ruili 1ZHANG Jing1

作者信息

  • 1. Dept.of Pharmacy,Wangjing Hospital of Chinese Academy of Chinese Medical Sciences,Beijing 100102,China
  • 折叠

摘要

Abstract

OBJECTIVE:To investigate the influencing factors of medication compliance in hypertensive patients,analyze the influencing paths of medication compliance,so as to propose rational suggestions for improving the medication compliance in hypertensive patients.METHODS:A total of 488 hypertensive patients in the hospital that met the inclusion criteria from Dec.1st,2023 to Apr.1st,2024 were randomly selected for questionnaire survey.Univariate Logistic regression analysis was used to identify factors associated with medication compliance,multivariate Logistic regression analysis was used to identify independent factors influencing medication compliance and self-efficacy.Mplus 8.3 software was use to perform path analysis and construct medication compliance path diagram.RESULTS:The medication compliance rate of hypertensive patients was 44.5%(217/488),indicating a low level.The mediating path for medication compliance in hypertensive patients were as follows:age → sleep disorders/adverse reactions → medication compliance(indirect effect accounted for 23%),concerns about the adverse reactions of Chinese patent medicine → sleep disorders/adverse reactions → medication compliance(indirect effect accounted for 34%),administration of antihypertensive Chinese patent medicine → health education/clinician-patient communication → medication compliance(indirect effect accounted for 38%).CONCLUSIONS:Sleep disorders,adverse reactions,health education and clinician-patient communication mediate medication compliance.It is recommended that healthcare institutions should enhance health education for hypertensive patients,strengthen clinician-patient communication and establish evaluation systems for clinician-patient communication,patients should improve sleep quality and increase awareness of adverse drug reactions.

关键词

高血压/服药依从性/路径分析

Key words

Hypertension/Medication compliance/Path analysis

分类

医药卫生

引用本文复制引用

ZHANG Meizhu,ZHENG Jinfeng,SU Shuang,ZHANG Ruili,ZHANG Jing..基于安德森模型的高血压患者服药依从性影响因素的路径分析[J].中国医院用药评价与分析,2025,25(12):1437-1440,4.

基金项目

全国中药特色技术传承人才培训项目(No.国中医药人教函[2023]96号) (No.国中医药人教函[2023]96号)

中国医院用药评价与分析

1672-2124

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