中国现代医学杂志2026，Vol.36Issue(1)：16-21,6.DOI:10.3969/j.issn.1005-8982.2026.01.003
超声监测结合丁苯酞氯化钠对脑梗死介入治疗后再闭塞风险及神经功能恢复的影响研究
Effects of ultrasound monitoring combined with butylphthalide sodium chloride on the risk of reocclusion and neurological recovery after interventional therapy for cerebral infarction
摘要
Abstract
Objective To investigate the effects of ultrasound monitoring combined with butylphthalide sodium chloride on the risk of reocclusion and neurological recovery after interventional therapy for cerebral infarction.Methods A total of 92 patients who underwent interventional therapy for cerebral infarction in Xingtai Central Hospital from March 2023 to March 2025 were selected as the research subjects.They were divided into the control group and the observation group according to the random number table method,with 46 cases in each group.The control group was treated with butylphthalide sodium chloride;the observation group was treated with butylphthalide sodium chloride combined with ultrasound monitoring on the basis of the control group.The incidence of vascular reocclusion after thrombolysis,neurological function indices,hemodynamic parameters,and biomarkers of neuronal injury and repair were compared between the two groups.Results The incidence of vascular reocclusion in the observation group was significantly lower than that in the control group(P<0.05).The differences in the scores of National Institutes of Health Stroke Scale(NIHSS)and modified Rankin Scale(mRS)before and after treatment in the observation group were greater than those in the control group(P<0.05).The differences in cerebral blood flow(CBF),cerebral blood volume(CBV),and mean transit time(MTT)between pre-operation and 24 h post-operation in the observation group were higher than those in the control group(P<0.05).The differences in serum levels of glial fibrillary acidic protein(GFAP),calcium-binding protein B(S-100B),and neuron-specific enolase(NSE)before and after treatment in the observation group were greater than those in the control group(P<0.05).Conclusion Ultrasound monitoring combined with butylphthalide sodium chloride can effectively reduce the risk of reocclusion after interventional therapy for cerebral infarction,promote neurological recovery,improve cerebral blood perfusion,and is conducive to clinical promotion and application.关键词
脑梗死/介入治疗/超声监测/丁苯酞氯化钠/再闭塞/神经功能Key words
cerebral infarction/interventional therapy/ultrasound monitoring/butylphthalide sodium chloride/reocclusion/neurological function分类
医药卫生引用本文复制引用
Huang Jin,Huo Xu-ning,Zhang Rui-yan,Li Li-feng,Zhang Sai..超声监测结合丁苯酞氯化钠对脑梗死介入治疗后再闭塞风险及神经功能恢复的影响研究[J].中国现代医学杂志,2026,36(1):16-21,6.基金项目
河北省自然科学基金(No:H2022307073) （No:H2022307073）
邢台市科技局重点研发计划自筹项目(No:2024ZC206) （No:2024ZC206）
