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山胡椒属药用植物及其倍半萜类化合物的研究进展

GUO Jia-qi MA Run-chao SHI Qi MENG Xiong-yu QIN Lu-ping LI Hua-qiang

中国中药杂志2025,Vol.50Issue(24):6816-6832,17.
中国中药杂志2025,Vol.50Issue(24):6816-6832,17.DOI:10.19540/j.cnki.cjcmm.20250804.201

山胡椒属药用植物及其倍半萜类化合物的研究进展

Research progress on medicinal plants of genus Lindera and their sesquiterpenoids

GUO Jia-qi 1MA Run-chao 1SHI Qi 1MENG Xiong-yu 1QIN Lu-ping 1LI Hua-qiang1

作者信息

  • 1. School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou 311402,China
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摘要

Abstract

The genus Lindera,a member of the Lauraceae family,comprises numerous species with broad prospects for medicinal and edible use,and has been widely applied in traditional Chinese medicine(TCM).Modern studies show that the key constituents of Lindera plants include flavonoids,alkaloids,terpenoids,and lignans.Among them,sesquiterpenoids exhibit complex structural diversity and diverse skeletons,as well as a broad spectrum of pharmacological activities such as anti-tumor,anti-inflammatory,neuroprotective,and hepatoprotective effects,making them crucial bioactive compounds of this genus.This paper systematically examined the herbal authentication of medicinal Lindera species and reviewed 165 sesquiterpenoids that have been isolated to date,together with their pharmacological activities.These findings highlight the significant potential of sesquiterpenoids in drug discovery and development,offering valuable insights for the optimal utilization and sustainable development of Lindera plant resources.

关键词

山胡椒属/本草考证/化学成分/倍半萜/药理活性

Key words

Lindera/herbal authentication/chemical constituent/sesquiterpenoid/pharmacological activity

引用本文复制引用

GUO Jia-qi,MA Run-chao,SHI Qi,MENG Xiong-yu,QIN Lu-ping,LI Hua-qiang..山胡椒属药用植物及其倍半萜类化合物的研究进展[J].中国中药杂志,2025,50(24):6816-6832,17.

基金项目

国家自然科学基金项目(U2202213,32470248) (U2202213,32470248)

浙江中医药大学自然科学青年探索项目(2022JKZKTS08) (2022JKZKTS08)

中国中药杂志

OA北大核心

1001-5302

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