中医学报（英文）2025，Vol.5Issue(4)：206-212,7.DOI:10.1055/s-0045-1814091
丹皮酚治疗呼吸系统疾病的研究进展
Research Progress of Paeonol in the Treatment of Respiratory Diseases
摘要
Abstract
Paeonol is a natural phenolic compound found in plants of the Ranunculaceae family,such as Mudanpi(Moutan Cortex)and Shaoyao(Paeoniae Radix).It possesses a wide range of pharmacological activities.Modern research confirms that paeonol exhibits various pharmacological effects,including anti-inflammatory,antioxidant,antitumor,and immunomodulatory activities,demonstrating unique application value in the treatment of respiratory diseases.With the recent development of nanodelivery systems and derivatives,issues such as low oral bioavailability,poor stability,and short half-life of paeonol have been significantly improved.This article systematically reviews the role and mechanisms of paeonol in treating respiratory diseases such as asthma,pulmonary fibrosis,chronic obstructive pulmonary disease(COPD),lung cancer,allergic rhinitis,and pneumonia,analyzing existing application problems and potential solutions,aiming to provide a theoretical basis for its clinical application and further research and development.关键词
丹皮酚/呼吸系统疾病/药理活性/牡丹皮/芍药Key words
paeonol/respiratory diseases/review/pharmacological activity/Mudanpi(Moutan Cortex)/Shaoyao(Paeoniae Radix)引用本文复制引用
Yuwei Song,Xixi Wang,Bofei Yang,Liu Yang,Yanqin Qin..丹皮酚治疗呼吸系统疾病的研究进展[J].中医学报（英文）,2025,5(4):206-212,7.基金项目
National Natural Science Foundation of China(82104662),Natural Science Foundation of Henan Province(252300420126),International Science and Technology Cooperation Project of Henan Province(252102521022),and Science and Technology Tackling Project of Henan Province(242102311251). （82104662）
