中医学报（英文）2025，Vol.5Issue(4)：213-225,13.DOI:10.1055/s-0045-1814435
泽泻的化学成分和药理作用研究进展
Research Progress on Chemical Constituents and Pharmacological Effects of Zexie(Alismatis Rhizoma)
Wanbing Shang 1Bian Wang 2Haoyue Yuan 2Linlin Li2
作者信息
- 1. School of Forensic Medicine,Henan Medical University,Xinxiang,Henan,China||Xinxiang Medical University Judicial Appraisal Center,Xinxiang,Henan,China
- 2. Xinxiang Medical University Judicial Appraisal Center,Xinxiang,Henan,China
- 折叠
摘要
Abstract
As a diuretic and dampness-eliminating medicinal agent in traditional Chinese medi-cine(TCM),Zexie(Alismatis Rhizoma)is commonly used for symptoms such as dysuria,edema and abdominal distension,diarrhea with oliguria,and dizziness due to phlegm-fluid retention.Systematic phytochemical studies have revealed that the active components of Zexie(Alismatis Rhizoma)are primarily triterpenoids,along with sesquiterpenes,polysaccharides,sterols,alkaloids,phenolic acids,and lignans.These components form the material basis for its pharmacological activities.Recent break-throughs in pharmacological research have expanded beyond its traditionally recog-nized diuretic and anti-inflammatory effects:Its antiurolithiasis effect has been clearly linked to inhibiting the crystallization of stone components and promoting stone expulsion;its renal protective effect can ameliorate kidney injury by reducing oxidative stress and suppressing inflammatory responses in renal tissues;its lipid-lowering mechanism involves regulating lipid metabolism pathways and reducing lipid deposi-tion;in terms of anticancer activity,it exhibits proliferation inhibition and apoptosis induction in various tumor cells such as liver,lung,and colon cancers;additionally,it shows significant antibacterial activity against pathogens,including Escherichia coli and Staphylococcus aureus.关键词
泽泻/化学成分/药理作用/中药Key words
Alismatis Rhizoma/Zexie/chemical constituents/pharmacological effects/review引用本文复制引用
Wanbing Shang,Bian Wang,Haoyue Yuan,Linlin Li..泽泻的化学成分和药理作用研究进展[J].中医学报（英文）,2025,5(4):213-225,13.
