湖南中医杂志2025，Vol.41Issue(12)：18-21,4.DOI:10.16808/j.cnki.issn1003-7705.2025.12.004
白及粉灌肠联合美沙拉嗪口服治疗大肠湿热型溃疡性结肠炎67例
Clinical effect of enema with Bletilla striata powder combined with mesalazine in treatment of ulcerative colitis with large intestine damp-heat type:An analysis of 67 cases
摘要
Abstract
Objective:To investigate the clinical effect of enema with Bletilla striata powder combined with mesalazine in the treatment of ulcerative colitis with large intestine damp-heat type.Methods:A total of 132 patients with mild or moderate ulcerative colitis were randomly divided into treatment group with 67 patients and con-trol group with 65 patients.The patients in the control group were given oral administration of mesalazine sustained-release granules alone,while those in the treatment group were given enema with Bletilla striata powder in addition to the treatment in the control group;both groups were treated for 4 consecutive weeks.The two groups were com-pared in terms of symptom score and inflammation parameters,and clinical outcome was assessed for both groups.Results:There was a significant difference in overall response rate between the treatment group and the control group[94.03(63/67)vs 84.62(55/65),P＜0.05].After treatment,both groups had significant changes in symptom score and inflammation parameters,and there were significant differences in these indicators between the two groups(P＜0.05).Conclusion:In the treatment of ulcerative colitis with large intestine damp-heat type,enema with Bletilla striata powder combined with mesalazine can improve clinical symptoms,reduce the levels of inflamma-tion parameters,and promote mucosa healing,with a better clinical effect than mesalazine used alone.Therefore,it holds promise for clinical application.关键词
溃疡性结肠炎/大肠湿热型/白及粉/中药灌肠/炎症因子Key words
ulcerative colitis/large intestine damp-heat type/Bletilla striata powder/traditional Chinese medicine enema/inflammatory factors分类
医药卫生引用本文复制引用
司中华,丁洋..白及粉灌肠联合美沙拉嗪口服治疗大肠湿热型溃疡性结肠炎67例[J].湖南中医杂志,2025,41(12):18-21,4.
