湖南中医杂志2025，Vol.41Issue(12)：22-26,5.DOI:10.16808/j.cnki.issn1003-7705.2025.12.005
半夏泻心汤加减联合枸橼酸莫沙必利片治疗糖尿病胃轻瘫30例
Clinical effect of modified Banxia Xiexin decoction combined with mosapride citrate tablets in treatment of diabetic gastroparesis:An analysis of 30 cases
摘要
Abstract
Objective:To investigate the clinical effect of modified Banxia Xiexin decoction combined with mosapride citrate tablets in the treatment of diabetic gastroparesis(DGP),as well as its impact on blood glucose,blood lipid and bone metabolism.Methods:A total of 60 patients with DGP were randomly divided into treat-ment group and control group,with 30 patients in each group.The patients in the control group were given mosapride citrate tablets,while those in the treatment group were given modified Banxia Xiexin decoction in addition to the treatment in the control group,and the course of treatment was 8 consecutive weeks for both groups.The two groups were compared in terms of gastric emptying rate,traditional Chinese medicine(TCM)symptom score,blood glucose,blood lipids,and bone metabolism markers before and after treatment;adverse reactions were recorded,and clinical outcome was assessed.Results:The treatment group had a significantly higher overall response rate than the control group[93.33％(28/30)vs 76.67％(23/30),P＜0.05].After treatment,both groups had significant changes in gastric emptying rate,TCM symptom score,blood glucose parameters,blood lipid parameters,and bone metabolism markers,and there were significant differences in these indicators between the two groups after treatment(P＜0.05).There was no significant difference in the incidence rate of adverse reactions between the treat-ment group and the control group[13.33％(4/30)vs 6.67％(2/30),P＞0.05].Conclusion:In the treatment of DGP,modified Banxia Xiexin decoction combined with mosapride citrate tablets can significantly improve clinical outcome,gastric emptying function,and TCM symptoms and optimize blood glucose,blood lipid metabolism,and bone metabolism,with a good safety profile.关键词
糖尿病胃轻瘫/半夏泻心汤/枸橼酸莫沙必利/胃排空率/中医症状/血糖/血脂/骨代谢Key words
diabetic gastroparesis/Banxia Xiexin decoction/mosapride citrate tablets/gastric emptying rate/traditional Chinese medicine symptom/blood glucose/blood lipids/bone metabolism分类
医药卫生引用本文复制引用
张翔..半夏泻心汤加减联合枸橼酸莫沙必利片治疗糖尿病胃轻瘫30例[J].湖南中医杂志,2025,41(12):22-26,5.基金项目
湖南省常德市科技创新项目(2023ZD109) （2023ZD109）
