口腔疾病防治2026，Vol.34Issue(1)：86-95,10.DOI:10.12016/j.issn.2096-1456.202550282
压电材料的抗菌性能及其在口腔医学领域的应用
Antibacterial properties of piezoelectric materials and their applications in stomatology
摘要
Abstract
Microbial infections are a prevalent challenge in the prevention and treatment of oral diseases.Antibiotic therapy faces clinical limitations due to its single-target mechanism and tendency to induce resistance with repeated use,necessitating novel antibacterial strategies.Stimuli-responsive antibacterial materials,whose antimicrobial activity can be modulated by external stimuli,offer advantages such as remote controllability,potential for localized precision treatment,and a reduced risk of inducing resistance.Among these materials,mechanical force-triggered piezoelectric materials exhibit significant antibacterial activity in the biomedical field owing to their unique piezoelectric effect,ex-cellent stability,and good biocompatibility.Research has shown that piezoelectric materials can convert mechanical en-ergy into electrical energy in response to external forces,which enables antibacterial effects without requiring an exter-nal power source.The underlying mechanisms primarily include direct electric field effects,generation of reactive oxy-gen species,and immune modulation.Preliminary applications in treating oral infections(e.g.,dental caries,periodonti-tis,and peri-implantitis)have confirmed their stability and biocompatibility,establishing a foundation for clinical trans-lation.However,long-term efficacy and biosafety in the complex oral microenvironment require further validation.Fu-ture research should focus on optimizing material preparation protocols to enhance antibacterial efficacy and stability,further investigating the underlying antimicrobial mechanisms,and systematically evaluating their therapeutic outcomes and safety profiles across various types of oral infections.This review summarizes the antibacterial effects,mechanisms,stability,safety,and research progress of piezoelectric materials in the stomatologic field,aiming to provide new insights for further research and application in this area.关键词
刺激响应性/压电材料/压电效应/抗菌作用/抗菌机制/稳定性/安全性/口腔医学Key words
stimuli-responsive/piezoelectric materials/piezoelectric effect/antibacterial activity/antibacte-rial mechanism/stability/safety/stomatology分类
医药卫生引用本文复制引用
张淑军,王秀清,黄晓晶..压电材料的抗菌性能及其在口腔医学领域的应用[J].口腔疾病防治,2026,34(1):86-95,10.基金项目
福建省卫健委科技计划项目(2022CXA043) （2022CXA043）
福建省科技联合创新基金项目(2021Y9026) This study was supported by the grants from the Fujian Provincial Health Technology Project(No.2022CXA043)and the Joint Funds for the Innovation of Science and Technology of Fujian Province(No.2021Y9026). （2021Y9026）
