国际老年医学杂志2026，Vol.47Issue(1)：32-37,6.DOI:10.3969/j.issn.1674-7593.2026.01.005
膳食抗氧化指数与老年冠心病患者冠状动脉狭窄程度的关系
Relationship between dietary antioxidant index and degree of coronary artery stenosis in elderly patients with coronary heart disease
摘要
Abstract
Objective To investigate the association between dietary antioxidant index(DAI)and the degree of coronary artery stenosis and prognosis in elderly patients with coronary heart disease.Methods 206 elderly patients who underwent coronary angiography from January 2022 to January 2024 were included and divided into a CHD group(coronary artery stenosis≥50%,62 ca-ses)and a control group(coronary artery stenosis<50%,144 cases)according to the degree of stenosis.The CHD group was further divided into single(20 cases),double(27 cases)and three(15 cases)subgroups according to the number of lesions.Food frequency questionnaire was used to calculate the DAI score,logistic regression was used to analyze the relationship between DAI and multi-vessel lesions,and the coronary heart disease group(57 cases)was followed up for a median of 12 months,and the independent association between DAI and major cardiovascular adverse events(MACE)was analyzed by a multivariate logistic regression model.Results The DAI score of the coronary heart disease group was lower than that of the control group(P<0.05),and the DAI score decreased with the increasing number of coronary artery disease lesions(P<0.05).Multivariate logistic regression showed that a decreased DAI score was one of the independent risk factors for multi-vessel lesions in patients with coronary heart disease(P<0.05).Follow-up showed that 57 patients were followed up.The lower the DAI bisection in elderly patients with coronary heart disease,the higher the incidence of MACE.The multivariate logistic regression indicated that the DAI score was a protective factor affecting the occurrence of MACE(P<0.05).Age,≥3 vessel lesions and low-density lipoprotein cholesterol were all independent risk factors affecting the occurrence of MACE(P<0.05).Conclusion The DAI score of elderly patients with coronary heart disease is significantly correlated with the degree of coronary artery stenosis and poor prognosis.Low DAI is an independent predictor of multi-vessel disease and MACE,sugges-ting that dietary antioxidant capacity may delay the progression of coronary artery disease by reducing oxidative stress,providing a new basis for dietary intervention.关键词
冠心病/膳食抗氧化指数/冠状动脉狭窄Key words
Coronary heart disease/Dietary antioxidant index/Coronary artery stenosis引用本文复制引用
陈武君,董毅,叶巧仪..膳食抗氧化指数与老年冠心病患者冠状动脉狭窄程度的关系[J].国际老年医学杂志,2026,47(1):32-37,6.基金项目
国家卫健委"十三五"规划重点课题(NHFPC102018) （NHFPC102018）
2023年东莞市社会发展科技重点项目(20231800940162) （20231800940162）
