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牙髓干细胞在牙槽骨再生中的成骨作用及影响因素

丁成兴 李小兰 杨明理

国际口腔医学杂志2026,Vol.53Issue(1):43-50,8.
国际口腔医学杂志2026,Vol.53Issue(1):43-50,8.DOI:10.7518/gjkq.2026201

牙髓干细胞在牙槽骨再生中的成骨作用及影响因素

Osteogenic effect and factors that influence dental pulp stem cells in alveolar bone regeneration

丁成兴 1李小兰 2杨明理1

作者信息

  • 1. 遵义医科大学基础医学院 遵义 563000
  • 2. 遵义医科大学口腔医学院 遵义 563000
  • 折叠

摘要

Abstract

Dental pulp stem cells(DPSCs)have potential for self-renewal and differentiation into various cell types.They can be transplanted into the defect area of the alveolar bone to induce their differentiation into osteoblasts,thereby promoting the regeneration and reconstruction of the alveolar bone.This study reviews the osteogenic ability of DPSCs in alveolar bone regeneration and the factors that influence their osteogenic ability.The challenges faced in the clinical appli-cation of DPSCs are analyzed to provide insights into the basic research and clinical application of DPSCs for repairing the alveolar bone.

关键词

牙髓干细胞/牙槽骨/骨缺损/骨再生

Key words

dental pulp stem cell/alveolar bone/bone defect/bone regeneration

分类

医药卫生

引用本文复制引用

丁成兴,李小兰,杨明理..牙髓干细胞在牙槽骨再生中的成骨作用及影响因素[J].国际口腔医学杂志,2026,53(1):43-50,8.

基金项目

Project of Zunyi Science and Technology Department(Zunyi Science and Technology Cooperation Project HZ[2020]36) (Zunyi Science and Technology Cooperation Project HZ[2020]36)

Project of Guizhou Province Science and Technology Department(Guizhou Science and Technology Coo-peration[2018]5772-043) (Guizhou Science and Technology Coo-peration[2018]5772-043)

2023 Science and Technology Fund Project of Guizhou Provincial Health Commission(gz-wkj2023-520) 遵义市科技计划项目(遵市科合HZ字2020-36) (gz-wkj2023-520)

遵义医科大学2018年度学术新苗培养及创新探索专项项目(黔科合平台人才[2018]5772-043) (黔科合平台人才[2018]5772-043)

2023 年度贵州省卫生健康委科学技术基金(gzwkj2023-520) (gzwkj2023-520)

国际口腔医学杂志

1673-5749

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