广州中医药大学学报2026，Vol.43Issue(1)：1-7,7.DOI:10.13359/j.cnki.gzxbtcm.2026.01.001
基于因子分析和聚类分析探讨病毒性急性肺损伤的中医证候规律
Exploring the Patterns of Traditional Chinese Medicine Syndromes in Viral Acute Lung Injury Based on Factor Analysis and Cluster Analysis
摘要
Abstract
Objective To investigate the distribution patterns of traditional Chinese medicine(TCM)syndromes in patients with viral acute lung injury(VALI),providing an objective reference for the clinical standardization and precise treatment based on syndrome differentiation.Methods A retrospective collection of general information and TCM four-examination information from 222 VALI patients hospitalized in the Department of Respiratory and Critical Care Medicine at Dongguan Hospital of Guangzhou University of Chinese Medicine(Dongguan Hospital of Traditional Chinese Medicine)between July 2021 and August 2024 was conducted.Data were extracted,organized,and entered into an Excel spreadsheet.Factor analysis and cluster analysis were employed for statistical analysis to summarize the distribution patterns of TCM syndromes in VALI patients.Results Frequency analysis of the TCM four-examination information from the 222 VALI patients identified 36 symptoms or signs closely related to VALI.The top 10 most frequent were wheezing and shortness of breath,cough,yellow purulent sputum,chest distress and oppression,yellow and greasy tongue coating,thirst with desire to drink,slippery pulse,red tongue,chest pain,and yellow-white sputum.Through factor analysis and cluster analysis,four TCM syndrome types were ultimately identified:phlegm-heat obstructing the lung syndrome(43.24%),heat-toxin attacking the lung syndrome(27.93%),deficiency of both qi and yin syndrome(19.82%),and healthy qi deficiency with panting-induced prostration syndrome(9.01%).Conclusion The distribution of TCM syndromes in VALI patients is primarily characterized by excess syndromes such as phlegm-heat obstructing the lung syndrome and heat-toxin attacking the lung syndrome,while deficiency syndromes mainly manifest as deficiency of both qi and yin syndrome and critical qi deficiency with respiratory collapse syndrome.The disease location is mainly in the lung,involving the spleen,kidney,and heart.The key pathological factors are"heat","toxin","phlegm"and"deficiency",with particular emphasis on"heat"and"phlegm".关键词
病毒性急性肺损伤/中医证候/痰热壅肺证/热毒袭肺证/气阴两虚证/正虚喘脱证/因子分析/聚类分析分类
医药卫生引用本文复制引用
谢林,宋栋,陈余姗,黄海阳,王凯,连乐燊..基于因子分析和聚类分析探讨病毒性急性肺损伤的中医证候规律[J].广州中医药大学学报,2026,43(1):1-7,7.基金项目
国家自然科学基金资助项目(编号:82274381) （编号:82274381）
国家中医药传承创新科研专项基金资助项目(编号:2022QN24) （编号:2022QN24）
