金刚石与磨料磨具工程2025，Vol.45Issue(6)：759-768,10.DOI:10.13394/j.cnki.jgszz.2024.0051
单颗粒掺硼金刚石电极的制备及其氨基酸检测应用
Preparation of single particle boron-doped diamond electrodes and their application in electrochemical detection of amino acid
摘要
Abstract
Objectives:The work aims to investigate the effect of boron doping levels on the electrochemical perform-ance of single boron-doped diamond(BDD)microparticle electrodes,and to explore their potential application for elec-trochemical detection of electroactive amino acids.Methods:The technology of hot filament chemical vapor deposition(HFCVD)is used to grow polycrystalline BDD films on a single crystal BDD.To ensure the uniformity of the film,the growth process is repeated three times with each deposition process lasting for 6 hours.By altering the flow ratio of bor-ane in the gaseous source,with the volume ratios of 0.1,0.15,and 0.2,different BDD microparticle electrodes are ob-tained,labeled as BDD-1,BDD-2,and BDD-3.The surface morphology and phase composition of the BDD micro-particle electrodes are characterized by scanning electron microscopy(SEM)and Raman spectroscopy respectively.The basic electrochemical performance of the BDD microparticle electrodes is systematically investigated,including electro-chemical window,electron transfer kinetic constant(k0),electrochemically active surface area(SECSA)and charge trans-fer resistance(Rct).Cyclic voltammetry(CV)and differential pulse voltammetry(DPV)are used to assess the electro-chemical properties of the BDD microparticle electrodes for detection of Trp,Tyr and Met.The detection sensitivity of the BDD microparticle electrodes to these amino acids is assessed by the method of chronoamperometry.Results:When the flow ratio of borane was 0.1,the surface of BDD-1 is rough and the diamond grain size is small,and the boron-doped concentration is 7.71×1020 cm-3.When the flow ratio is increased to 0.15,the grain size is slightly increased,and some regions of BDD-2 grew grains with clear crystal faces and obvious grain boundaries,but there are still uneven sizes and some crystal faces are rough,and the boron-doped concentration is 1.12×1021 cm-3.When the flow ratio is ad-justed to 0.2,the grains on the surface of BDD-3 are complete,the crystal surface are smooth,the grain boundary are clearer,the grains grow densely and uniformly in size,and the boron-doped concentration is 2.02×1021 cm-3.The ob-tained electrochemical potential windows of BDD-1,BDD-2 and BDD-3 particle electrodes are 3.50,3.31 and 3.05 V,and k0 is calculated to be 4.87×10-4,5.25×10-4 and 6.30×10-4 cm·s-1,respectively.The SECSA is 0.66,0.69 and 0.89 mm2,and the Rct is 4.45,3.12 and 0.92 kΩ,respectively.The oxidation peak potentials of Trp,Tyr and Met are 0.76,0.65 and 1.36 V,respectively.With the increase of boron concentration,the oxidation peak current increases gradually.The detection sensitivity of the BDD-3 microparticle electrodes for electrochemical detection of Trp,Tyr and Met is obtained to be 16.6,137.8 and 131.4 µA·(mmol/L)-1·cm-2,respectively.Conclusions:The results show that in-creasing the boron concentration within a certain range can effectively improve the film quality of BDD,accelerate the electron transfer kinetic rate of the BDD microparticle electrodes,reduce the charge transfer resistance,and improve the overall electrochemical activity of the electrodes.The proposed BDD microparticle electrodes have good electrochemic-al detection ability for three amino acids(Trp,Tyr and Met),among which they have high detection sensitivity for Tyr and Met.The effect of Trp on electrode adsorption at high concentrations is an important issue to be addressed in sub-sequent studies.关键词
掺硼金刚石/电化学性能/电化学传感器/热丝化学气相沉积/氨基酸Key words
boron-doped diamond/electrochemical performance/electrochemical sensor/hot filament chemical vapor deposition/amino acid分类
数理科学引用本文复制引用
李静,王润,于睿智,窦金杰,邓泽军,马莉,魏秋平..单颗粒掺硼金刚石电极的制备及其氨基酸检测应用[J].金刚石与磨料磨具工程,2025,45(6):759-768,10.基金项目
国家"十四五"重点研究发展计划(2021YFB3701800) （2021YFB3701800）
国家自然科学基金资助项目(52202056,52274370,52071345,51874370) （52202056,52274370,52071345,51874370）
广东省"十三五"重点研究开发项目(2020B01085001) （2020B01085001）
湖南省高新技术产业科技创新引领计划(2022GK4037,2022GK4047) （2022GK4037,2022GK4047）
湖南省自然科学基金资助项目(2023JJ40722) （2023JJ40722）
粉末冶金国家重点实验室自主课题(621022230). （621022230）
