健康研究2025，Vol.45Issue(6)：645-649,5.DOI:10.19890/j.cnki.issn1674-6449.2025.06.009
基于肠道菌群探讨不同饮食模式对肥胖症患者脂代谢的影响
Effects of different dietary patterns on lipid metabolism in obesity:a perspective based on gut microbiota
摘要
Abstract
Obesity,as a metabolic disorder,can induce inflammation and insulin resistance,leading to various chronic diseases.The prevalence of obesity in China has been rising annually,posing a substantial societal burden.Dysbiosis of gut microbiota is commonly observed in obese individuals,and gut microbiota is closely linked to host lipid metabolism.Different dietary patterns exert distinct influences on gut microbiota,thereby affecting the development and progression of obesity,which highlights the potential of microbiotatargeted dietary interventions for obesity management.This review outlines the characteristics and metabolic mechanisms of gut microbiota in obesity and further summarizes how three representative dietary patterns—the Mediterranean diet(MD),ketogenic diet(KD),and highfiber diet(HFD)—modulate lipid metabolism through the gut microbiota.The aim is to provide evidence and references for dietary interventions in obesity.关键词
肥胖/肠道菌群/代谢产物/脂质代谢/饮食模式Key words
obesity/gut microbiota/metabolites/lipid metabolism/dietary pattern分类
医药卫生引用本文复制引用
俞迪雯,张鹏炜,李力..基于肠道菌群探讨不同饮食模式对肥胖症患者脂代谢的影响[J].健康研究,2025,45(6):645-649,5.基金项目
浙江省科技计划项目(2022C03138) （2022C03138）
杭州市医药卫生科技项目(A20240256) （A20240256）
