上海针灸杂志2026，Vol.45Issue(1)：28-32,5.DOI:10.13460/j.issn.1005-0957.2026.01.0028
隔姜药灸治疗缓解期溃疡性结肠炎的疗效观察及对肠道菌群的影响
Efficacy observation of ginger-insulated moxibustion in treating remission-stage ulcerative colitis and its impact on gut microbiota
摘要
Abstract
Objective To observe the clinical efficacy of ginger-insulated moxibustion at Shenque(CV8)in treating remission-stage ulcerative colitis(UC)and its impact on gut microbiota.Method Seventy-two patients with remission-stage UC were randomized into an observation group and a control group,with 36 cases in each group.The control group received oral administration of Mesalazine enteric-coated tablets,and the observation group was treated with ginger-insulated moxibustion at Shenque in addition to the control group's intervention.Before and after the treatment,the two groups were observed for changes in the serum level of C-reactive protein(CRP)and gut microbiota counts.The clinical efficacy was also compared between the two groups.Result The total effective rate was higher in the observation group(91.7%)than in the control group(72.2%)(P＜0.05).After intervention,the serum CRP level decreased in both groups(P＜0.05)and was lower in the observation group than in the control group(P＜0.05).After the treatment,the two groups showed decreased counts of Escherichia coli and Enterococci(P＜0.05)and increased counts of Bacteroides,Clostridia,Lactobacilli,and Bifidobacteria(P＜0.05);the observation group was superior to the control group(P＜0.05).Conclusion Based on Western medicine,ginger-insulated moxibustion at Shenque is effective in treating remission-stage UC,which can reduce intestinal inflammatory responses and balance gut microbiota.关键词
灸法/间接灸/隔姜灸/结肠炎,溃疡性/脾肾阳虚/C反应蛋白/肠道菌群Key words
Moxibustion/Indirect moxibustion/Ginger-partitioned moxibustion/Colitis,Ulcerative/Yang deficiency of spleen and kidney/C-reactive protein/Gut microbiota分类
医药卫生引用本文复制引用
许金钗,许宝才,刘建阳..隔姜药灸治疗缓解期溃疡性结肠炎的疗效观察及对肠道菌群的影响[J].上海针灸杂志,2026,45(1):28-32,5.基金项目
浙江省中医药科学研究项目(2021ZB327) （2021ZB327）
衢州市指导性科技计划项目(2021079) （2021079）
